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Product Image-EDVO135

Using CRISPR to treat cystic fibrosis

Catalog Number: (EDVO135)
Supplier: EDVOTEK
Description: Hands-on simulation of CRISPR-Cas9 to target and treat Cystic Fibrosis.
UOM: 1 * 1 KIT
Product Image-763-0007

Kits: why do people look different?, Ready-to-Load™

Catalog Number: (763-0007)
Supplier: EDVOTEK
Description: This kit is for teaching students how people's physical traits are a reflection of their genes. In this simulation, students use electrophoresis to separate dyes which represent genetic traits.
UOM: 1 * 1 KIT

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Product Image-EDVO110

Experimentation kits, molecular weight determination of proteins (agarose-based)

Catalog Number: (EDVO110)
Supplier: EDVOTEK
Description: This experiment introduces a simple method to determine protein subunit molecular weights using horizontal electrophoresis. As the protein standards and 'unknowns' are prestained, the separation of proteins can be observed during electrophoresis. Included in the experiment is protein-grade agarose, which provides an alternative to the use of polyacrylamide gels.
UOM: 1 * 1 KIT
Product Image-EDVO101

Kits: principles and practice of agarose gel electrophoresis, Ready-to-Load™

Supplier: EDVOTEK
Description: Ready-to-Load™ kit to show how electrophoresis separates molecules on the basis of size and charge.

Product Image-763-0010

Kits: the mystery of the crooked cell, Ready-to-Load™

Catalog Number: (763-0010)
Supplier: EDVOTEK
Description: This simple experiment demonstrates detection of the mutation that causes Sickle Cell Anaemia. In this simulation, students use electrophoresis to separate dyes that represent patient samples and controls.
UOM: 1 * 1 items
Product Image-EDVO315

Kits: in search of the sickle cell gene by southern blot, Ready-to-Load™

Catalog Number: (EDVO315)
Supplier: EDVOTEK
Description: Southern blotting is an important technique used widely in clinical genetics and research. By transferring DNA from an agarose gel onto a membrane the method allows the precise analysis and identification of DNA bands on a gel. Using this kit, students use Southern blotting to find a point mutation in the haemoglobin gene indicating Sickle Cell Anaemia.
UOM: 1 * 1 items

MSDS


Product Image-EDVO115-C

Kits: family pedigree cancer gene detection, Ready-to-Load™

Supplier: EDVOTEK
Description: In this experiment, students determine a pedigree for a family thought to be carriers of a mutation in their p53 genes. This is followed by a diagnostic agarose gel analysis to diagnose the state of the p53 gene in individual family members.

Product Image-EDVO105-C

Kits: mapping of restriction sites on plasmid DNA, Ready-to-Load™

Supplier: EDVOTEK
Description: DNA mapping is a common procedure used to determine the location of genes. In this experiment, DNA markers and pre-digested plasmid DNA fragments are mapped using agarose gel electrophoresis.

Product Image-BE-409

Experimentation kits, conservation of genetic information

Catalog Number: (BE-409)
Supplier: G-Biosciences
Description: In this lab activity, students learn to perform carefully controlled experiments to generate protein fragments using a proteolysis enzyme and then analyse the protein fragments by electrophoresis. By analysis of protein fragmentation patterns, i.e. protein fingerprints, students learn about protein sequence, structure, and their conservation. Students resolve a set of three functionally identical protein samples selected from throughout the animal kingdom; including human, bovine and sheep. After generating fingerprints by electrophoresis, students examine the protein fingerprint of each sample to determine the degree of conservation.
UOM: 1 * 1 KIT
Product Image-EDVO117-C

Kits: detection of mad cow disease, Ready-to-Load™

Supplier: EDVOTEK
Description: Bovine spongiform encephalophathy (BSE), also known as Mad Cow Disease, is a neurodegenerative, fatal condition in cattle. Consuming BSE-infected beef is believed to be the cause of a similar condition in humans, Creutzfeldt-Jakob disease. In this experiment, students examine simulated PCR products from several feed mills, to determine any possible violations of the ban on including animal parts in cattle feed.

Product Image-EDVO253

Experimentation kits, diversity of fish proteins

Catalog Number: (EDVO253)
Supplier: EDVOTEK
Description: In this experiment, students study the diversity of fish using pre-stained, lyophilised proteins. Total protein from perch, walleye and salmon is extracted and pre-stained using an indicator dye. Each fish protein sample has a characteristic banding pattern when separated by denaturing SDS-polyacrylamide gel electrophoresis, which can be used to identify the specific species.
UOM: 1 * 1 KIT
Product Image-EDVO316

Experimentation kits, in search of the cholesterol gene

Catalog Number: (EDVO316)
Supplier: EDVOTEK
Description: Coronary heart disease and stroke are major causes of death in the Western world. Elevated blood cholesterol levels are a serious risk factor in both conditions. The genetic disease familial hypersholesterolemia (FH) causes an increase in blood levels of the bad form of cholesterol, low density lipoprotein (LDL). In untreated patients with the mutant FH gene, the condition can cause premature death. This experiment introduces the colorimetric enzymatic reaction which is the basis of the clinical cholesterol test. In addition, using agarose gel electrophoresis, students can analyse a simulated genetic screening for a disease.
UOM: 1 * 1 KIT
Product Image-BE-314

Experimentation kits, mutation detection and analysis

Catalog Number: (BE-314)
Supplier: G-Biosciences
Description: A major challenge for molecular biologists and genetic engineers is to easily detect and analyze genetic mutations that occur naturally, causing diseases, or during genetic engineering or cloning, whether deliberate or accidental. Students learn about different types of genetic mutations, including substitutions, deletions and point mutations and about various techniques used to detect genetic mutations. The kit contains all the reagents to screen simulated clinical samples for a mutant gene, using both the polymerase chain reaction (PCR) and restriction digestion mapping. Students conduct a simple clinical diagnostic experiment in order to identify a diseased patient.
UOM: 1 * 1 KIT
Product Image-EDVO908

Experimentation kits, introduction to plant cell culture

Catalog Number: (EDVO908)
Supplier: EDVOTEK
Description: Genetic modification of plants is a controversial area of biotechnology. All such experiments in plants begin with establishing plant cells in culture. This involves de-differentiating plant cells to form plant 'stem cells'. In this experiment, students establish cell cultures of African violets from leaves. They then use plant growth regulators to encourage root growth from the cultured cells, and produce a mature plant.
UOM: 1 * 1 KIT
Product Image-BE-301

Experimentation kits, bacterial conjugation

Catalog Number: (BE-301)
Supplier: G-Biosciences
Description: Bacterial conjugation is a naturally occurring process that allows the transfer of DNA from one bacterium to another, which allows the transfer of genetic traits, particularly drug resistance. The kit contains two bacteria with different drug resistance genes and all the tools for students to study bacterial conjugation. This kit teaches the difference between bacterial genomic DNA and the transferable plasmid DNA and the mechanisms of bacterial conjugation. Students will also learn important basic microbiological techniques, including bacterial growth in liquid broth and on solid agar plates, antibiotic selection of bacteria and important aseptic techniques.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-11870R-A350

Anti-LHX5 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11870R-A350)
Supplier: Bioss
Description: During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The human LHX5 gene maps to chromosome 12q23-q24 and encodes a 402 amino acid protein. The hippocampus contains the neural circuitry, which is crucial for cognitive functions such as learning and memory. LHX5 regulates precursor cell proliferation and neuronal differentiation and migration during hippocampal development.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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