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You Searched For: HAT+activator,+CTPB


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Image Unavailable-ENZOBMLSE4530010

Human recombinant Cathepsin S

Catalog Number: (ENZOBMLSE4530010)
Supplier: ENZO LIFE SCIENCES
Description: Highly active
UOM: 1 * 10 µG
Image Unavailable-BOSSBS-9452R-CY3

Anti-RGS4 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-9452R-CY3)
Supplier: Bioss
Description: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1478R-CY5

Anti-PAFR Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1478R-CY5)
Supplier: Bioss
Description: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0049R-FITC

Anti-CASP9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0049R-FITC)
Supplier: Bioss
Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0049R-A350

Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-0049R-A350)
Supplier: Bioss
Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2449R-CY5.5

Anti-TNFRSF9 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2449R-CY5.5)
Supplier: Bioss
Description: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1789R-FITC

Anti-IL12A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1789R-FITC)
Supplier: Bioss
Description: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1789R-A680

Anti-IL-12 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-1789R-A680)
Supplier: Bioss
Description: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3549R-A680

Anti-KSR1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3549R-A680)
Supplier: Bioss
Description: Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
UOM: 1 * 100 µl
Product Image-ENZOBMLPE1900010

Farnesyl thiotriazole ≥98% (by TLC)

Catalog Number: (ENZOBMLPE1900010)
Supplier: ENZO LIFE SCIENCES
Description: PKC activator.
UOM: 1 * 10 mg
Image Unavailable-BOSSBS-0049R-A680

Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-0049R-A680)
Supplier: Bioss
Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Product Image-ABCAAB133479-100

Anti-Ube1L+E1 Ubiquitin Activating Enzyme 1/UBA1 Rabbit Monoclonal Antibody [clone: EPR4269(2)]

Supplier: Abcam
Description: Rabbit monoclonal [EPR4269(2)] to Ube1L + E1 Ubiquitin Activating Enzyme 1/UBA1.

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Image Unavailable-BOSSBS-2485R-A555

Anti-JAK2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-2485R-A555)
Supplier: Bioss
Description: JAK2 (Janus Activating Kinase 2) is a tyrosine kinase of the non-receptor type, that associates with the intracellular domains of cytokine receptors; JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin; it has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon. Ligand binding to a variety of cell surface receptors (e.g., cytokine, growth factor, GPCRs) leads to an association of those receptors with JAK proteins, which are then activated via phosphorylation on tyrosines 1007 and 1008 in the kinase activation loop. Activated JAK proteins phosphorylate and activate STAT (signal transducers and activators of transcription) proteins, which then dimerize and translocate to the nucleus. Once in the nucleus, STAT proteins bind to DNA and modify the transcription of various genes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3029R-CY7

Anti-MAP3K5 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3029R-CY7)
Supplier: Bioss
Description: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3021R-A647

Anti-ALK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3021R-A647)
Supplier: Bioss
Description: Neuronal orphan receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis and differentiation of the nervous system. Transduces signals from ligands at the cell surface, through specific activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. Following activation by ligand, ALK induces tyrosine phosphorylation of CBL, FRS2, IRS1 and SHC1, as well as of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Acts as a receptor for ligands pleiotrophin (PTN), a secreted growth factor, and midkine (MDK), a PTN-related factor, thus participating in PTN and MDK signal transduction. PTN-binding induces MAPK pathway activation, which is important for the anti-apoptotic signaling of PTN and regulation of cell proliferation. MDK-binding induces phosphorylation of the ALK target insulin receptor substrate (IRS1), activates mitogen-activated protein kinases (MAPKs) and PI3-kinase, resulting also in cell proliferation induction. Drives NF-kappa-B activation, probably through IRS1 and the activation of the AKT serine/threonine kinase. Recruitment of IRS1 to activated ALK and the activation of NF-kappa-B are essential for the autocrine growth and survival signaling of MDK.
UOM: 1 * 100 µl
Product Image-ABCAAB225441-100

Anti-active YAP1 Rabbit Monoclonal Antibody [clone: EPR19812] (Alexa Fluor® 488)

Catalog Number: (ABCAAB225441-100)
Supplier: Abcam
Description: Alexa Fluor® 488 Rabbit monoclonal [EPR19812] to active YAP1.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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