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Anti-ALKBH1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-12565R-CY3)

Supplier: Bioss

Description: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

UOM: 1 * 100 µl

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Ferroin (1,10-phenanthrolineferrous sulphate complex) solution indicator, for COD determination

Catalog Number: (HACH181233)

Supplier: Hach

Description: Oxidation-reduction indicator solution used in determination of COD by ferrous titration.

UOM: 1 * 29 mL

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Ferroin (1,10-phenanthrolineferrous sulphate complex) solution indicator, for COD determination (low range)

Catalog Number: (HACH2055133)

Supplier: Hach

Description: Oxidation-reduction indicator solution used in determination of COD, low range, by ferrous titration.

UOM: 1 * 25 mL

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Anti-SDHB Rabbit Polyclonal Antibody

Catalog Number: (PRSI26-268)

Supplier: ProSci Inc.

Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

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Anti-FTL Mouse Monoclonal Antibody [clone: FTL/1386]

Catalog Number: (PRSI33-711)

Supplier: ProSci Inc.

Description: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UOM: 1 * 100 µG

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