You Searched For: Iron+boride

Supplier: ENZO LIFE SCIENCES

Description: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Catalog Number: (BOSSBS-11788R-A350)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Supplier: Merck

Description: Aminoferrocene ≥98.0% (by titrimetric analysis) derivatisation reagent, for HPLC, Supelco®

Catalog Number: (BOSSBS-11788R-A647)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11788R-FITC)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11788R-A750)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11788R-A680)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0988R-HRP)

Supplier: Bioss

Description: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

UOM: 1 * 100 µl

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Supplier: Merck

Description: <B>All Spectroquant® test kits</B> can be used with the <B>Prove</B> range of spectrophotometers and Nova 60/60A instruments. Tests can be used not only on photometers and spectrophotometer from Merck, but also on photometers and spectrophotometers from other suppliers (programming details available on request). <B>Spectroquant® cell test kits.</B>

MSDS Sale

Supplier: ENZO LIFE SCIENCES

Description: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Catalog Number: (USBI128577)

Supplier: US Biological

Description: Anti-IREB2 Mouse Polyclonal Antibody

UOM: 1 * 50 µG

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Catalog Number: (BOSSBS-6053R-CY5)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-6053R-CY7)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11788R-A488)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-6053R-A350)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-6053R-CY3)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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