You Searched For: Electrical+Meters

Catalog Number: (BOSSBS-0988R-CY5.5)

Supplier: Bioss

Description: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

UOM: 1 * 100 µl

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Supplier: Thermo Fisher Scientific

Description: Potassium trioxalatoferrate(III) trihydrate

MSDS Certificates

Supplier: ENZO LIFE SCIENCES

Description: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Catalog Number: (USBI128578)

Supplier: US Biological

Description: Anti-IREB2 Mouse Monoclonal Antibody [clone: 1F3]

UOM: 1 * 100 µG

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Catalog Number: (BOSSBS-15417R-CY7)

Supplier: Bioss

Description: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-15417R-A647)

Supplier: Bioss

Description: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-15417R-A488)

Supplier: Bioss

Description: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11788R-A555)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Supplier: SIGMA ALDRICH MICROSCOPY

Description: N,N-Dimethyl-p-phenylenediamine dihydrochloride (DMPD) has been used in the HID-AB (high iron diamine-alcian blue) staining of intestinal tract samples. N,N-Dimethyl-p-phenylenediamine dihydrochloride (DMPD) is used for the determination of peroxidase. DMPD is converted into a red pigment of semiquinone nature. It is also used in the HID-AB (high iron diamine-alcian blue) staining procedures, which are used to differentiate between sialomucin and sulfomucin in the gastrointestinal tract.

Catalog Number: (BOSSBS-0988R-FITC)

Supplier: Bioss

Description: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-8468R-A680)

Supplier: Bioss

Description: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-8468R-A750)

Supplier: Bioss

Description: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-6053R-CY5)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-6053R-CY7)

Supplier: Bioss

Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Supplier: VWR Collection

Description: H-shaped stands with nickel-coated steel rod and 420×400 mm grey marbled cast iron baseplate.

Catalog Number: (BOSSBS-11788R-CY7)

Supplier: Bioss

Description: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

Sale