You Searched For: LJI-308

Catalog Number: (BOSSBS-2739R)

Supplier: Bioss

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5545R)

Supplier: Bioss

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5545R-A750)

Supplier: Bioss

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-2739R-FITC)

Supplier: Bioss

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

UOM: 1 * 100 µl

Sale

Catalog Number: (BOSSBS-5545R-FITC)

Supplier: Bioss

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11359R-A488)

Supplier: Bioss

Description: Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.

UOM: 1 * 100 µl

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Catalog Number: (ABNOMAB10081)

Supplier: Abnova

Description: Mouse monoclonal antibody raised against TRITC.

UOM: 1 * 200 µG

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Supplier: MAPA

Description: These natural latex gloves with textile lining provide good comfort for long-term work in food processing environments.

Catalog Number: (BURK0301-0500)

Supplier: BURKLE

Description: HDPE, translucent, with PP screw cap.

UOM: 1 * 1 items

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Catalog Number: (BIBB701-28)

Supplier: SciLabware

Description: Screwthread tubes, Sealing rings for sliding joints, silicone rubber sheathed with PTFE, SVL® joint size 42, for tubing O.Ø 29,2 - 30,8 mm

UOM: 1 * 10 items

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Catalog Number: (UPCHP-308)

Supplier: UPCHURCH SCIENTIFIC

Description: Upchurch Scientific®, P-308, flangeless short nuts, delrin black/ETFE yellow, 1/4-28 flat bottom port, standard knurl, for 1/8" OD tubing, 500 psi, ETFE

UOM: 1 * 1 items

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Catalog Number: (AMARH841668-FL)

Supplier: Amarell

Description: Hydrometers with thermometer for boiler feed water according to Doctor Ammer.

UOM: 1 * 1 items

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Catalog Number: (BROE17.160.009)

Supplier: BROEN-LAB

Description: Wall recessed eye shower with anti-corrosive cabinet.

UOM: 1 * 1 items

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Catalog Number: (MANA732984FE)

Supplier: MACHEREY-NAGEL

Description: CHROMABOND®, CHROMABOND® Flash DL 80, PE filter elements, 30,8 mm ID

UOM: 1 * 250 items

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Catalog Number: (DGINBT074)

Supplier: DGP INTELSIUS

Description: Intelsius® Biotherm packaging systems are regulatory compliant to IATA, ADR, and 49 CFR (DOT) transport regulations. These shippers utilise dry ice to maintain sample integrity during shipments from 24 to 240 hours.

UOM: 1 * 1 items

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Catalog Number: (ABNOMAB10082)

Supplier: Abnova

Description: Mouse monoclonal antibody raised against TRITC.

UOM: 1 * 200 µG

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