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Image Unavailable-BNC040771-100

Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: DCS-72.F6]

Description: Recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Catalog Number: BNC040771-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BNC041237-500

Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: SX53G8]

Description: This antibody recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Catalog Number: BNC041237-500
UOM: 1 * 500 µl
Supplier: Biotium
Image Unavailable-BOSSBS-1437R-CY5

Anti-MRP5/ABCC5 Rabbit Polyclonal Antibody (Cy5®)

Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
Catalog Number: BOSSBS-1437R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-4901R-CY7

Anti-ANXA7 Rabbit Polyclonal Antibody (Cy7®)

Description: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
Catalog Number: BOSSBS-4901R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BNUB1228-100

Anti-CD6 Mouse Monoclonal Antibody [clone: C6/372 3F7B5]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNUB1228-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BOSSBS-1437R-A488

Anti-MRP5/ABCC5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
Catalog Number: BOSSBS-1437R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BNC680372-500

Anti-CD6 Mouse Monoclonal Antibody (CF568) [clone: C6/372]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNC680372-500
UOM: 1 * 500 µl
Supplier: Biotium
Image Unavailable-BNC040372-100

Anti-CD6 Mouse Monoclonal Antibody (CF405S) [clone: C6/372]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNC040372-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BNC940428-100

Anti-CD6 Mouse Monoclonal Antibody (CF594) [clone: 3F7B5]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNC940428-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BNC680428-100

Anti-CD6 Mouse Monoclonal Antibody (CF568) [clone: 3F7B5]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNC680428-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BNC040428-100

Anti-CD6 Mouse Monoclonal Antibody (CF405S) [clone: 3F7B5]

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Catalog Number: BNC040428-100
UOM: 1 * 100 µl
Supplier: Biotium
Image Unavailable-BOSSBS-8563R

Anti-KIAA1522 Rabbit Polyclonal Antibody

Description: KIAA1522 is a 1,035 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p35.1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: BOSSBS-8563R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BNUB0437-500

Anti-CD47 Mouse Monoclonal Antibody (Purified) [clone: B6H12.2]

Description: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Catalog Number: BNUB0437-500
UOM: 1 * 500 µl
Supplier: Biotium
Image Unavailable-BOSSBS-6096R-FITC

Anti-RNF139 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Catalog Number: BOSSBS-6096R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-7514R-A350

Anti-ADGRB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.
Catalog Number: BOSSBS-7514R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-20333-50UL

Anti-IgG Chicken Polyclonal Antibody (CF™ 543)

Description: CF™543 antibodies are affinity-purified antibodies labeled with orange fluorescent CF™543 (Ex/Em 541/560nm), a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
Catalog Number: 20333-50UL
UOM: 1 * 50 µl
Supplier: Biotium
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