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Image Unavailable-BOSSBS-9553R-FITC

Anti-FAM127A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-9553R-FITC)
Supplier: Bioss
Description: The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXX1 gene product has been provisionally designated CXX1 pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9553R-CY7

Anti-FAM127A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9553R-CY7)
Supplier: Bioss
Description: The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXX1 gene product has been provisionally designated CXX1 pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9082R-A680

Anti-AKIRIN2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-9082R-A680)
Supplier: Bioss
Description: Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8246R-A555

Anti-CADM2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-8246R-A555)
Supplier: Bioss
Description: Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0676R-CY7

Anti-FGFR4 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0676R-CY7)
Supplier: Bioss
Description: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes SRC-dependent phosphorylation of the matrix protease MMP14 and its lysosomal degradation. FGFR4 signaling is down-regulated by receptor internalization and degradation; MMP14 promotes internalization and degradation of FGFR4. Mutations that lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1805R-HRP

Anti-IL6RA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-1805R-HRP)
Supplier: Bioss
Description: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1980R-HRP

Anti-MASP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-1980R-HRP)
Supplier: Bioss
Description: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
UOM: 1 * 100 µl
Image Unavailable-ENZOADICSA509E

Anti-SARM Rabbit Polyclonal Antibody

Catalog Number: (ENZOADICSA509E)
Supplier: Enzo Life Sciences
Description: SARM (SAM and ARM-containing protein) is thought to serve as an adaptor protein for the Toll-like receptors (TLRs) and allow for the activation of downstream kinases and NF-κB, ultimately leading to the expression of proteins involved in host defense.
UOM: 1 * 100 µG
Image Unavailable-129-2619

Rigid Conductive Boxes

Supplier: DESCO
Description: Desco Europe Rigid Conductive Boxes are marked with the ESD protective symbol. Boxes can be supplied with or without high density foam for insertion of component leads or low density foam which acts as a cushioning material.

Image Unavailable-BOSSBS-0676R-A750

Anti-FGFR4/CD334 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-0676R-A750)
Supplier: Bioss
Description: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes SRC-dependent phosphorylation of the matrix protease MMP14 and its lysosomal degradation. FGFR4 signaling is down-regulated by receptor internalisation and degradation; MMP14 promotes internalisation and degradation of FGFR4. Mutations that lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3210R-FITC

Anti-JUN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-3210R-FITC)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5458R-FITC

Anti-JUN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-5458R-FITC)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0670R-A647

Anti-JUN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-0670R-A647)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0670R-HRP

Anti-JUN Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0670R-HRP)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0670R-FITC

Anti-JUN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0670R-FITC)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Product Image-BOHLR9125-02

Starter set, b.safe Multiport II

Catalog Number: (BOHLR9125-02)
Supplier: Bohlender
Description: One connection for collecting liquid waste from up to 2 HPLC systems that can be integrated directly in laboratory hoods or working tables. b.safe Waste Tubes lead liquid solvent waste directly into connected canisters.
UOM: 1 * 1 SET
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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