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Product Image-SIOE699Z/A41/M

Rain trousers, Murray 699Z

Supplier: SIOEN
Description: Highly breathable rain trousers made of Siopor® Regular fabric consisting of 100% polyester fabric (plain weave) with water-repellent PU coating. With fixed mesh lining and taped seams.

Product Image-STMC78059.2

Mouse Recombinant M-CSF (E.coli-expressed)

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitors to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux andamp; Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam andamp; Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam andamp; Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).

Product Image-STMC78057.1

Human Recombinant M-CSF (E.coli-expressed)

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux and Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam and Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam and Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).

Product Image-STMC78150.1

Human Recombinant M-CSF, ACF

Supplier: STEMCELL Technologies
Description: Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitors to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux andamp; Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam andamp; Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam andamp; Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>). This product is animal component-free.

Image Unavailable-MURRG801/03

Bottles, alpha

Supplier: MURRAY S
Description: Capacity: 150 ml

Product Image-MURR2081/01

Stethoscope popular

Catalog Number: (MURR2081/01)
Supplier: MURRAY S
Description: Stethoscope, dual headed
UOM: 1 * 1 items
Product Image-MURRP023/04

Accessories for aspirator bottles with screw caps and stopcock

Catalog Number: (MURRP023/04)
Supplier: MURRAY S
Description: Spare screw on tap
UOM: 1 * 1 items
Product Image-233-0018

Household scissors

Supplier: MURRAY S
Description: Stainless steel.

Image Unavailable-MURRL330/21

Test tube stands

Supplier: MURRAY S
Description: Hardwood, with plastic ends.

Image Unavailable-G850/03

Watch glasses

Supplier: MURRAY S
Description: Made of glass.

Image Unavailable-G501/02

Dressing jars

Supplier: MURRAY S
Description: Dressing jars, made of moulded glass, round.

Product Image-233-0011

Dissecting scissors, straight

Supplier: MURRAY S
Description: Stainless steel.

Image Unavailable-G826/04

Funnels

Supplier: MURRAY S
Description: Funnels,made of moulded glass, with plain pattern.

Product Image-E108/01

Dissecting scissors, curved tip

Supplier: MURRAY S
Description: Stainless steel.

Image Unavailable-MURRL026/03

Pipeclay triangles

Supplier: MURRAY S
Description: Pipeclay stems on stout wire.

Image Unavailable-L602/01

Wooden applicator

Catalog Number: (L602/01)
Supplier: MURRAY S
Description: Wooden applicator stick.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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