You Searched For: 2-Bromoacrylic+acid

Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.

Catalog Number: BOSSBS-7048R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalisation and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.

Catalog Number: BOSSBS-7048R-A680

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Cyanidin-3-O-galactoside chloride 95% min

Catalog Number: APOSBICL4237-5MG

UOM: 1 * 5 mg

Supplier: Apollo Scientific

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Description: 2-Deoxy-D(-)-ribose 99%

Catalog Number: ACRO153280050

UOM: 1 * 5 g

Supplier: Thermo Fisher Scientific

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Description: Potassium xanthogenate (potassium-O-ethyl dithiocarbonate) for synthesis, Sigma-Aldrich®

Catalog Number: 8.20744.0500

UOM: 1 * 500 g

Supplier: Merck

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Description: N-Octyl-β-D-glucopyranoside

Catalog Number: DG016

UOM: 1 * 5 g

Supplier: G-Biosciences

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Description: Potassium hexafluorosilicate, Supelco®

Catalog Number: 60322-1KG

UOM: 1 * 1 kg

Supplier: Merck

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Description: β-D-Maltose octaacetate 98%

Catalog Number: A12988.14

UOM: 1 * 25 g

Supplier: Thermo Fisher Scientific

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Description: <p>Hellma® large cells for special applications in the Vis range, 10 to 50 mm path length, with or without lid.</p>

Catalog Number: HELL740-000-10

UOM: 1 * 1 items

Supplier: HELLMA

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Description: D-(+)-Melezitose monohydrate

Catalog Number: APOSBIB6097-250G

UOM: 1 * 250 g

Supplier: Apollo Scientific

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Description: Resveratrol 99%

Catalog Number: APOSOR46018-100G

UOM: 1 * 100 g

Supplier: Apollo Scientific

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Description: Isoflavone derived from Soybean.

Catalog Number: APOSBIG3110-25MG

UOM: 1 * 25 mg

Supplier: Apollo Scientific

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Description: Ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside ≥99%

Catalog Number: APOSBICL4095-5G

UOM: 1 * 5 g

Supplier: Apollo Scientific

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Description: 4-Methoxyphenyl-2,3,4,6-tetra-O-acetyl-β-D-glucopyanoside 99% min

Catalog Number: APOSBICL4135-5G

UOM: 1 * 5 g

Supplier: Apollo Scientific

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Description: Non-ionic detergent used for membrane protein solubisation.

Catalog Number: APOSBIMB1375-5G

UOM: 1 * 5 g

Supplier: Apollo Scientific

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Description: These precision ground-joint thermometers are suitable for official certification.

Catalog Number: SCNL1302212

UOM: 1 * 1 items

Supplier: Ludwig Schneider GmbH & CO. KG

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