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Image Unavailable-BOSSBS-13507R-A350

Anti-GPR84 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression.
Catalog Number: BOSSBS-13507R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13507R-A555

Anti-GPR84 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression.
Catalog Number: BOSSBS-13507R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1325R-A647

Anti-PDE4D Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.
Catalog Number: BOSSBS-1325R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13518R-A350

Anti-ADGRG7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
Catalog Number: BOSSBS-13518R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13517R-FITC

Anti-ADGRG7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
Catalog Number: BOSSBS-13517R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13517R-A488

Anti-ADGRG7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
Catalog Number: BOSSBS-13517R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13517R-A555

Anti-ADGRG7 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
Catalog Number: BOSSBS-13517R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-2139R-A647

Anti-GRM2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Catalog Number: BOSSBS-2139R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3603R

Anti-VASP Rabbit Polyclonal Antibody

Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Catalog Number: BOSSBS-3603R
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3603R-HRP

Anti-VASP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Catalog Number: BOSSBS-3603R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-3603R-A647

Anti-VASP Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Catalog Number: BOSSBS-3603R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11891R-CY3

Anti-MTPN Rabbit Polyclonal Antibody (Cy3®)

Description: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.
Catalog Number: BOSSBS-11891R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11891R-FITC

Anti-MTPN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.
Catalog Number: BOSSBS-11891R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-8277R-CY5

Anti-GPRIN3 Rabbit Polyclonal Antibody (Cy5®)

Description: May be involved in neurite outgrowth.G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/action, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, and are involved in many pathological conditions. GRIN3 (G protein-regulated inducer of neurite outgrowth 3), also known as GPRIN3, is a 776 amino acid protein that contains a C-terminal region which shares a high homology with GRIN2 and GRIN1, and may function in neurite outgrowth.
Catalog Number: BOSSBS-8277R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-MDTC46-011-CM

10X TBE buffer, liquid, Corning®

Description: TBE (Tris-Borate-EDTA) has applications in DNA and RNA agarose gel electrophoresis and polyacrylamide gel electrophoresis.
Catalog Number: MDTC46-011-CM
UOM: 1 * 6 items
Supplier: Corning

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Product Image-PIER28374

Pierce™ BupH™ Wash Buffers, Dry Blend Pack

Description: BupH packs are pre-blended and pre-measured dry mixtures of buffers that are easy to prepare and used in protein purification and common laboratory techniques.
Catalog Number: PIER28374
UOM: 1 * 40 items
Supplier: Thermo Fisher Scientific
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