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Product Image-BSBTPB9280

Anti-Lamin A/C Polyclonal Antibody

Description: Polyclonal antibody for LAMIN A/LMNA detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. LAMIN A/LMNA information: Molecular Weight: 74139 MW; Subcellular Localization: Nucleus. Nucleus envelope. Nucleus lamina. Nucleus, nucleoplasm. Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleaveage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin- A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C; Tissue Specificity: In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress.
Catalog Number: BSBTPB9280
UOM: 1 * 100 µG
Supplier: Boster Bio
Product Image-PRSI28-894

Anti-ATF1 Rabbit Polyclonal Antibody

Description: ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Catalog Number: PRSI28-894
UOM: 1 * 50 µG
Supplier: ProSci Inc.
Product Image-ICNA111002200

DNA purification kits, GeneClean® for Ancient DNA™ Kit, MP Biomedicals

Description: The GeneClean® for Ancient DNA™ Kit is ideal for purification of fragmented or damaged DNA from aged or preserved samples. It is designed for isolation of up to 20 μg DNA from bone, preserved tissue, soil organisms, or animal by-products.
Catalog Number: ICNA111002200
UOM: 1 * 1 KIT
Supplier: MP Biomedicals
Image Unavailable-CAYM10010811-10

Lutein ≥98%, crystalline solid

Description: Lutein (Xanthophyll) is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. It is a lipid-soluble antioxidant that can circulate in the plasma and confer cardioprotective, anti-inflammatory, and anti-angiogenic effects. Dietary lutein, in combination with zeaxanthin, vitamins and ω-3 fatty acids, may be beneficial against age-related macular degeneration and cataract development.
Catalog Number: CAYM10010811-10
UOM: 1 * 10 mg
Supplier: Cayman Chemical

MSDS


Product Image-PRSI28-895

Anti-ATF1 Rabbit Polyclonal Antibody

Description: ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Catalog Number: PRSI28-895
UOM: 1 * 50 µG
Supplier: ProSci Inc.
Product Image-PRSI29-611

Anti-AGER Rabbit Polyclonal Antibody

Description: AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.
Catalog Number: PRSI29-611
UOM: 1 * 100 µG
Supplier: ProSci Inc.
Product Image-PRSI27-324

Anti-ATF1 Rabbit Polyclonal Antibody

Description: ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Catalog Number: PRSI27-324
UOM: 1 * 50 µG
Supplier: ProSci Inc.
Product Image-OZBIGXS0003

Senescence kit

Description: Senescence kit allows visualisation of aging cells and is ideal when cells in culture show abnormalities typical of the Hayflick limit after a long period of normal growth. The cells vary in size and shape, the cytoplasm begins to be granular with many cell inclusions and debris formed in the medium.
Catalog Number: OZBIGXS0003
UOM: 1 * 1 KIT
Supplier: OZ BIOSCIENCES
Image Unavailable-USBIO8061-100

Osteoclast inhibitory lectin MAB MO XMO

Description: Osteocrin is a recently identified secreted protein expression of which was only detected in bone, peaking just after birth and decreasing markedly with age. A 1280-bp mRNA encodes osteocrin producing a mature protein of 103 amino acids with a molecular mass of 11,4 kD. In primary osteoblastic cell cultures osteocrin expression coincided with matrix formation then decreased in very mature cultures.
Catalog Number: USBIO8061-100
UOM: 1 * 100 µG
Supplier: US Biological
Product Image-1.51468.0001

HPLC columns, Chromolith®

Description: Monolithic silica technology: A new age in chromatography. Chromolith® columns are based on silica so existing methods can be easily transferred with only minimal investment in new method development work. 'Sol-Gel' technology allows highly porous monolithic rods of silica to be formed. These feature a bimodal pore structure provides a unique combination of macropores and mesopores.
Catalog Number: 1.51468.0001
UOM: 1 * 1 items
Supplier: Merck

MSDS


Product Image-BOSSBS-6643R

Anti-GORAB Rabbit Polyclonal Antibody

Description: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
Catalog Number: BOSSBS-6643R
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-ACSDM8A96.1.5N.L1

Multi-element quality control standards for ICP

Description: ICP QC standards used for Al, Ag, As, B, Ba, Be, Bi, Ca, Cd, Cs, Co, Cr, Cu, Fe, In, K, Li, Mg, Mn, Mo, Na, Ni, Nb, Pb, Rb, Sb, Se, Sr, Ti, Tl, V, U, Zn. 1 mg/l for 33 elememts.
Catalog Number: ACSDM8A96.1.5N.L1
UOM: 1 * 100 mL
Supplier: CPACHEM
Image Unavailable-BOSSBS-6643R-A750

Anti-SCYL1BP1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterised by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
Catalog Number: BOSSBS-6643R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Product Image-EDVOS-91

Experimentation kits, whose fingerprints were left behind?

Description: Evidence left behind at a crime scene can identify a potential culprit. Even in this age of DNA, fingerprints and blood stains are still important in helping to identify a criminal. In this experiment, students solve a crime by dusting for fingerprints and use fluorescent dust to search for and identify trace amounts of blood.
Catalog Number: EDVOS-91
UOM: 1 * 1 items
Supplier: EDVOTEK

MSDS


Image Unavailable-PRSI91-440

Human recombinant LYPD3 (from cells)

Description: Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.
Catalog Number: PRSI91-440
UOM: 1 * 50 µG
Supplier: ProSci Inc.
Image Unavailable-BOSSBS-6643R-HRP

Anti-GORAB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
Catalog Number: BOSSBS-6643R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
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