You Searched For: Methyl+trans-3-bromocyclobutane-1-carboxylate


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Catalog Number: (277878-5G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Methyl-3-amino-5,6-dichloropyrazine-2-carboxylate 97%, Sigma-Aldrich®
UOM: 1 * 5 g


Catalog Number: (MOLE45298012-25G)
Supplier: Molekula
Description: trans-4-Hydroxy-L(-)-proline
UOM: 1 * 25 g

Market Source Item This is a MarketSource item. Additional charges may apply

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Supplier: Thermo Scientific
Description: Methyl-5-norbornene-2,3-dicarboxylic anhydride (mixture of isomers), tech.
Catalog Number: (EDQMT1810000)
Supplier: EDQM
Description: trans-4-(Aminomethyl)cyclohexanecarboxylic acid
UOM: 1 * 50 mg


Supplier: Apollo Scientific
Description: Naturally occurring (1'S)-(+) enantiomer of abscisic acid. Important sesquiterpenoid plant hormone, acts as a regulator of plant responses to environmental stresses. Roles as growth regulator, abscisic acid receptor agonist, plant metabolite.

Catalog Number: (BOSSBS-4281R-CY7)
Supplier: Bioss
Description: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
UOM: 1 * 100 µl


Catalog Number: (ROTH3893.1)
Supplier: Roth Carl
Description: trans-4-Hydroxy-L(-)-proline
UOM: 1 * 5 g

Market Source Item This is a MarketSource item. Additional charges may apply

Supplier: Thermo Scientific
Description: (2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid

New Product

Catalog Number: (8.41878.0005)
Supplier: Merck
Description: 3-Methylflavone-8-carboxylic acid ≥98% for synthesis, Sigma-Aldrich®
UOM: 1 * 5 g

MSDS


Supplier: Apollo Scientific
Description: (S)-Methyl 1-Tritylaziridine-2-carboxylate

Supplier: Apollo Scientific
Description: Methyl-1-benzylpiperidine-4-carboxylate

New Product

Supplier: Apollo Scientific
Description: Methyl benzimidazole-5-carboxylate

Supplier: Apollo Scientific
Description: Methyl isoquinoline-3-carboxylate

Catalog Number: (BOSSBS-4281R-A555)
Supplier: Bioss
Description: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-4281R-A680)
Supplier: Bioss
Description: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilises p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilisation and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilising the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
UOM: 1 * 100 µl


Supplier: Apollo Scientific
Description: Methyl tetrahydropyran-4-carboxylate

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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