You Searched For: Methyl-N-acetyl-L-tryptophanate

Catalog Number: (APOSOR7220T-10MG)

Supplier: Apollo Scientific

Description: Inhibitor of bacterial, animal and viral sialidases.

UOM: 1 * 10 mg

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Catalog Number: (PRSI50-242)

Supplier: ProSci Inc.

Description: Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin) (Martinez et al., 2001). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II) (Jiang et al., 2000; Johansen et al., 1996). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2 (McKinney et

UOM: 1 * 100 µl

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Supplier: Apollo Scientific

Description: 1-Acetyl-2,3-dihydro-N-[1-(2-phenylethyl)piperidin-4-yl]-1H-indole-5-amine 95+%

Supplier: Apollo Scientific

Description: 1,2-Di-O-acetyl-3,5-di-O-benzoyl-β-D-ribofuranose ≥99%

Supplier: Apollo Scientific

Description: 2,4-Di-O-acetyl-1,6-anhydro-3-O-benzyl-β-L-idopyranose ≥99%

Supplier: Apollo Scientific

Description: 1,6:2,3-Dianhydro-4-O-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-β-D-mannopyranose ≥99%

Catalog Number: (ENZOBMLL1340001)

Supplier: ENZO LIFE SCIENCES

Description: PAF receptor ligand.

UOM: 1 * 1 mg

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Catalog Number: (PRSI28-013)

Supplier: ProSci Inc.

Description: Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.

UOM: 1 * 50 µG

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Supplier: Apollo Scientific

Description: Ethyl 4-acetyl-1-cyclopropyl-2,5-dimethyl-1H-pyrrole-3-carboxylate

Catalog Number: (ENZOBMLEI1500005)

Supplier: ENZO LIFE SCIENCES

Description: Inhibits protein kinase C activation by diacylglycerols. Stimulates HL-60 cell differentiation. Biosynthetic precursor of PAF via remodeling and retroconversion/de novo routes. Induces delayed aggregation of rabbit platelets. Mitogenic for smooth muscle cells.

UOM: 1 * 5 mg

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Catalog Number: (PRSI91-280)

Supplier: ProSci Inc.

Description: There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.

UOM: 1 * 50 µG

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Supplier: Apollo Scientific

Description: 2,3,4-Tri-O-acetyl-1,6-diazido-1,6-dideoxy-β-D-glucopyranoside ≥98%

Catalog Number: (BOSSBS-6659R-A350)

Supplier: Bioss

Description: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.

UOM: 1 * 100 µl

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Catalog Number: (PRSI29-884)

Supplier: ProSci Inc.

Description: GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

UOM: 1 * 100 µG

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Catalog Number: (ROCK600-601-C96)

Supplier: Rockland Immunochemicals

Description: Anti-Tryptophan Hydroxylase (Sheep) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size.

UOM: 1 * 100 µl

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Supplier: Thermo Fisher Scientific

Description: 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose 96%

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