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Image Unavailable-ENZOADI905744100

Anti-Opioid Receptor mu Rabbit Polyclonal Antibody

Catalog Number: (ENZOADI905744100)
Supplier: ENZO LIFE SCIENCES
Description: The opioid receptors δ, κ, and μ are members of the seven-transmembrane domain-containing receptor family of G-protein coupled receptors. δ- and μ-receptors serve as functional receptors for endogenous enkephalin and β-endorphin peptide ligands, respectively. δ-opioid receptors are highly expressed in the olfactory bulb, neocortex, caudate putamen and nucleus accumbens, with peripheral expression in the gastro-intestinal tract and vas deferens. δ-receptors inhibit neurotransmitter release resulting in a variety of biological effects including analgesia, motor integration, gastro-intestinal motility, olfaction, respiration, and memory. Neural μ-receptor expression is prominent in the caudate putamen, neocortex, thalamus, nucleus accumbens, hippocampus, and amygdala, as well as in peripheral nervous tissues in the gut. Named for its pharmacological mediation of analgesia by morphine, the μ receptor typically functions as a depressant in physiological processes including respiration, cardiovascular function, gastrointestinal motility, and thermoregulation.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-13597R-CY5

Anti-HESX1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13597R-CY5)
Supplier: Bioss
Description: The homeobox protein, HESX1, which is also known as Rathke’s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11966R-CY5

Anti-SPOCK2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11966R-CY5)
Supplier: Bioss
Description: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-2 is expressed in the central nervous system (CNS), with widespread expression in the olfactory bulb, cerebral cortex, thalamus, hippocampus, cerebellum and medulla, and is also found in lung and testis. Testican-2 is unique in that it actually abolishes the inhibition of MT-MMPs by other testican family members and specifically inactivates N-Tes by binding to its COOH-terminal extracellular calcium-binding domain. Testican-2 halts neurite growth from cerebellar neurons and may be involved in regu-lating the development of the CNS.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11966R

Anti-SPOCK2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11966R)
Supplier: Bioss
Description: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-2 is expressed in the central nervous system (CNS), with widespread expression in the olfactory bulb, cerebral cortex, thalamus, hippocampus, cerebellum and medulla, and is also found in lung and testis. Testican-2 is unique in that it actually abolishes the inhibition of MT-MMPs by other testican family members and specifically inactivates N-Tes by binding to its COOH-terminal extracellular calcium-binding domain. Testican-2 halts neurite growth from cerebellar neurons and may be involved in regu-lating the development of the CNS.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12128R-CY5

Anti-ACCN2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12128R-CY5)
Supplier: Bioss
Description: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12128R-A488

Anti-ACCN2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12128R-A488)
Supplier: Bioss
Description: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.
UOM: 1 * 100 µl
Image Unavailable-630-0417

Accessories for stereo microscopes

Catalog Number: (630-0417)
Supplier: ZEISS
Description: Accessory for microscopes, For: SteREO Discovery.V8, Stage clip
UOM: 1 * 1 items
Product Image-631-1066

VWR® Q Path®, Slide Cabinet

Catalog Number: (631-1066)
Supplier: VWR Collection
Description: This cabinet, with lid, can be used in cytology and histology applications.
UOM: 1 * 10 items
Image Unavailable-BOSSBS-11072R-A488

Anti-ASTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-11072R-A488)
Supplier: Bioss
Description: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.
UOM: 1 * 100 µl
Image Unavailable-PERCN3050605

Electrodeless discharge lamps

Supplier: PerkinElmer
Description: These electrodeless discharge lamps are preferred for certain volatile elements. They offer better precision and lower detection limits for analyses that are 'noisy' due to weak hollow cathode emission. PerkinElmer system 2 EDLs consist of the element or a salt of the element sealed in a quartz bulb containing an inert gas atmosphere. When an RF field of sufficient power is applied, the inert gas is ionised and the coupled energy vaporizes the element and excites the atoms inside the bulb, resulting in the emission of the characteristic spectrum.

Product Image-630-1528

LED cold light source, KL 300 LED (without fan)

Catalog Number: (630-1528)
Supplier: SCHOTT AG Lighting and imaging
Description: This compact LED cold light source for eco-friendly PURAVIS® light guides is driven by a single LED and provides a brightness equivalent to a 30 W halogen lamp and is therefore ideal as a standard illumination system for the requirements of routine inspections and education.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-15047R-A555

Anti-C1orf187 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-15047R-A555)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15047R-HRP

Anti-C1orf187 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-15047R-HRP)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10392R-HRP

Anti-SYNGAP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-10392R-HRP)
Supplier: Bioss
Description: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
UOM: 1 * 100 µl
Product Image-12.220.300-45

Accessories for biological microscopes, BA 210 LED / BA210 Elite

Supplier: MOTIC
Description: Accessory for microscopes, Simple add on analyser

Image Unavailable-BOSSBS-15047R

Anti-C1orf187 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-15047R)
Supplier: Bioss
Description: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic β-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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