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Image Unavailable-BOSSBS-9742R-CY3

Anti-ANGEL2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-9742R-CY3)
Supplier: Bioss
Description: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3′–5′-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9742R-FITC

Anti-ANGEL2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-9742R-FITC)
Supplier: Bioss
Description: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3′–5′-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9742R-A488

Anti-ANGEL2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-9742R-A488)
Supplier: Bioss
Description: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3′–5′-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl
Product Image-BELAF378451000

Micro sieve set, Mini-Sieve™, SP Bel-Art

Catalog Number: (BELAF378451000)
Supplier: Bel-Art Products, a Part of SP
Description: PP holding set, phosphor-bronze mesh inserts. The set consists of four exchangeable screen holding segments, a catch pan, a cover and four screen retaining rings. Each storing segment of 29×51 mm can contain approximately 60 ml.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-0693R-CY5

Anti-NRP1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-0693R-CY5)
Supplier: Bioss
Description: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12254R-HRP

Anti-ZFP36L1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-12254R-HRP)
Supplier: Bioss
Description: TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3’-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12254R-A555

Anti-ZFP36L1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-12254R-A555)
Supplier: Bioss
Description: TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3’-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11742R-A555

Anti-DMPK Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11742R-A555)
Supplier: Bioss
Description: Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1). DMPK is implicated in myotonic muscular dystrophy (DM), an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2,3). DM arises through expansion of CTG repeats in the 3’-UTR of the DMPK gene (4). Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5). These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, to mediate in part the DM phenotype (6). Other substrates for DMPK include myogenin, L-type calcium channels, and Phospholemman (PLM) (1).
UOM: 1 * 100 µl
Image Unavailable-568-0479

Replacement mini union ferrules, SGE

Catalog Number: (568-0479)
Supplier: Trajan Scientific and Medical
Description: Replacement mini union ferrule, 15% graphite 85% vespel®, 0,3 mm hole, 15% graphite/85% Vespel®
UOM: 1 * 10 items
Image Unavailable-BOSSBS-11775R-HRP

Anti-ATXN8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11775R-HRP)
Supplier: Bioss
Description: Twinkle, also known as PEO1 (Progressive external ophthalmoplegia 1 protein), PEOA3, SANDO or TWINL, is a mitochondrial protein that functions as a 5’-3’ nucleotide-dependent DNA helicase. Colocalized with mtDNA (mitochondrial DNA) in mitochondrial nucleoids, Twinkle is important in the metabolism and maintenance of mtDNA, playing a crucial role in the regulation of mtDNA copy numbers. Twinkle is expressed at high levels in testis, pancreas and skeletal muscle and exists as three isoforms due to alternative splicing events. Defects in the gene encoding Twinkle are the cause of two conditions: progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant 3 (PEOA3) and sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO). PEOA3 is characterized by ptosis and weak muscles, while SANDO is characterized by ophthalmoparesis, dysarthria and sensory ataxic neuropathies.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12195R

Anti-HOXC6 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12195R)
Supplier: Bioss
Description: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups, which are dispersed over 4 chromosomes. HOX genes that occupy the same relative position along the 5’ to 3’ coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxC6 sequence-specific transcription factor is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. HOXC6 may be a novel potential therapeutic target for prostate cancer.
UOM: 1 * 100 µl
Product Image-1.14414.0001

Visual colour kits, copper, MQuant®, Supelco®

Supplier: Merck
Description: Quick tests for visual colour comparison.

MSDS

Image Unavailable-PHR1873-30MG

Pharmaceutical secondary standard, Atorvastatin Calcium and related compounds, (CRM), Supelco®

Catalog Number: (PHR1873-30MG)
Supplier: Merck
Description: Organic Standard, Atorvastatin Related Compound H
UOM: 1 * 30 mg
Product Image-RETS03.647.0368

Accessories for cyclone mill TWISTER

Supplier: Retsch GmbH
Description: Sieve section 2,0 mm, For: TWISTER, For: Cyclone mill TWISTER

Product Image-142-1131

Accessories for SONOREX ultrasonic baths

Supplier: BANDELIN-ELECTRONIC
Description: Ultrasonic bath accessories, Sieve holder SH 28 C, stainless steel, for simultaneous cleaning of upto five sieves of Ø 200 mm, For: SUPER RK 1028 C

Image Unavailable-H34443.06

2-Ethoxyacetyl chloride 97% stabilised

Supplier: Thermo Fisher Scientific
Description: Stab. with 0.3% Magnesium oxide

MSDS

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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