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Image Unavailable-BOSSBS-11308R

Anti-SRD5A1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11308R)
Supplier: Bioss
Description: Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone, which mediates androgen effects on target tissues. The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; and type 2, which is expressed mainly in the prostate. In cultured human skin cells, 5a-Reductase 1 shows heterogeneity of protein, and has different levels of transcriptional and translational expression. 5a-Reductase 1 is expressed in all portions of the hair follicle, whereas 5a-Reductase 2 is expressed only in mesenchymal portions. In addition, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma. The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.
UOM: 1 * 100 µl
Image Unavailable-8.41480.0250

4'-Chloroacetanilide for synthesis, Sigma-Aldrich®

Supplier: Merck
Description: 4'-Chloroacetanilide for synthesis, Sigma-Aldrich®

MSDS

Image Unavailable-ABCAAB275983-200

Anti-SARS Nucleocapsid Protein Rabbit Monoclonal Antibody [clone: CR3018 (03-018)]

Catalog Number: (ABCAAB275983-200)
Supplier: Abcam
Description: Anti-SARS Nucleocapsid Protein Rabbit Monoclonal Antibody [clone: CR3018 (03-018)]
UOM: 1 * 200 µG
Image Unavailable-53997-U

Supelco® Ascentis® Express C8 HPLC and UHPLC Columns

Supplier: Merck
Description: Ascentis® Express C8 high-speed, high-performance liquid chromatography columns are based on the highly efficient Fused-Core® particle design.

Image Unavailable-APOSPC52097-1G

4-(4-Fluorobenzyl)piperidine hydrochloride

Supplier: Apollo Scientific
Description: 4-(4-Fluorobenzyl)piperidine hydrochloride

Product Image-ACRO276721000

(S)-(+)-Camptothecin 98%

Supplier: Thermo Fisher Scientific
Description: CAS No.: 7689-03-4

MSDS Certificates

Image Unavailable-BOSSBS-11823R-A647

Anti-CSDC2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11823R-A647)
Supplier: Bioss
Description: PIPPIN is a Y-box protein (also called cold-shock (CSD) domain-containing protein) and belongs to a family of highly conserved RNA-binding transcriptional regulators. Predominantly expressed in brain cells and localizing to the nucleus and the cytoplasm, PIPPIN contains two RNA-binding motifs, namely PIP1 and PIP2, and one CSD domain. PIPPIN functions as a nucleic acid binding regulatory factor and is believed to participate in brain maturation. More specifically, PIPPIN binds to the 3’-UTR ends of the mRNAs encoding Histone H1 and Histone H3.3. This interaction requires all of the PIPPIN domains to work in concert as one functional protein. In addition, PIPPIN can be sumoylated in a thyroid hormone (T3)-dependent manner. This suggests that PIPPIN modification in response to extracellular stimuli may modulate the regulation of protein synthesis.
UOM: 1 * 100 µl
Image Unavailable-APOSOR9094-250MG

2-Vinylquinoline

Catalog Number: (APOSOR9094-250MG)
Supplier: Apollo Scientific
Description: 2-Vinylquinoline
UOM: 1 * 250 mg
Image Unavailable-BOSSBS-9742R-A555

Anti-ANGEL2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-9742R-A555)
Supplier: Bioss
Description: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3′–5′-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15573R

Anti-IGHD Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-15573R)
Supplier: Bioss
Description: Ig delta chain C region is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3’ side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events.
UOM: 1 * 100 µl
Image Unavailable-L03210.14

Methoxyacetyl chloride ≥97% stabilised

Supplier: Thermo Fisher Scientific
Description: Stabilized with ca 0.3% magnesium oxide

MSDS Certificates

Product Image-ROCK612-401-E22

Anti-RPH3A Rabbit Polyclonal Antibody

Catalog Number: (ROCK612-401-E22)
Supplier: Rockland Immunochemicals
Description: Anti-Rabpihilin 3A pS234 (Rabbit) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 82 kDa in size corresponding to rabphilin 3A Protein phosphorylated at Ser234.
UOM: 1 * 100 µl
Product Image-PRSI29-233

Anti-SF3B1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI29-233)
Supplier: ProSci Inc.
Description: SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
UOM: 1 * 100 µG
Image Unavailable-A13009.14

Tetrabromothiophene ≥99%

Supplier: Thermo Fisher Scientific
Description: Tetrabromothiophene ≥99%

MSDS Certificates

Product Image-AATB3007

Biotin hydrazide ≥95%

Catalog Number: (AATB3007)
Supplier: AAT BIOQUEST
Description: Biotin and biotin derivatives bind with high affinity to both avidins and streptavidins.
UOM: 1 * 25 mg
Product Image-30.022.0001

Analytical sieve shaker AS 400 control

Catalog Number: (30.022.0001)
Supplier: Retsch GmbH
Description: With horizontal circular motion, for sieves 100/150/200/203/305 and 400 mm diameter.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
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