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You Searched For: N-Hexanoyl-D-erythro-sphingosine


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Image Unavailable-BOSSBS-5587R-HRP

Anti-PIK3CD Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-5587R-HRP)
Supplier: Bioss
Description: Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation. Promotes cytokine production in response to TLR4 and TLR9. Required for antibody class switch mediated by TLR9. Involved in the antigen presentation function of B-cells. Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P). Required for proliferation, signaling and cytokine production of naive, effector and memory T-cells. Required for T-cell receptor (TCR) signaling. Mediates TCR signaling events at the immune synapse. Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues. Together with PIK3CG participates in T-cell development. Contributes to T-helper cell expansion and differentiation. Required for T-cell migration mediated by homing receptors SELL/CD62L, CCR7 and S1PR1 and antigen dependent recruitment of T-cells. Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in NK cell receptor activation. Have a role in NK cell maturation and cytokine production. Together with PIK3CG is involved in neutrophil chemotaxis and extravasation. Together with PIK3CG participates in neutrophil respiratory burst. Have important roles in mast-cell development and mast cell mediated allergic response. Involved in stem cell factor (SCF)-mediated proliferation, adhesion and migration.
UOM: 1 * 100 µl
Product Image-PRSI29-786

Anti-S1PR5 Rabbit Polyclonal Antibody

Catalog Number: (PRSI29-786)
Supplier: ProSci Inc.
Description: EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G (i/0)alpha and G (12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
UOM: 1 * 50 µG
Product Image-PRSI4809

Anti-S1P1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI4809)
Supplier: ProSci Inc.
Description: S1P1 Antibody: Movement of lymphocytes through lymphoid organs is required for generating immunity. Their migration into lymph nodes follows a series of events including integrin activation through chemokine signaling, adhesion and diapedis. The release of lymphocytes from lymph nodes is regulated by the phospholipid sphingosine-1-phosphate (S1P). One of its receptors S1P1 binds S1P with high specificity and affinity; agonism of this receptor by the immunosuppressive agent FTY720 inhibits the entry of tissue T cells into afferent lymphatics in homeostatic and inflammatory conditions. Recent experiments have indicated that CCR7-deficient T cells left lymph nodes more rapidly than wild-type cells did and these cells where also less effectively retained after treatment with FTY720, and that egress competence could be restored by inactivating G alpha i-protein-coupled receptor signaling. These results suggest that S1P1 acts in the lymphocyte to promote lymph node egress by overcoming retention signals mediated by CCR7 and G alpha i-protein-coupled receptor signaling.
UOM: 1 * 100 µG
Image Unavailable-CAYM10006822-1

Anti-SPHK1 Rabbit Polyclonal Antibody

Catalog Number: (CAYM10006822-1)
Supplier: Cayman Chemical
Description: Anti-SPHK1 Rabbit Polyclonal Antibody
UOM: 1 * 1 items
Image Unavailable-ABCAAB144090-100

N-HEXANOYL-NBD-D-ERYTHRO-SPHINGOSINE (C6 1 * 100 µG

Catalog Number: (ABCAAB144090-100)
Supplier: Abcam
Description: N-HEXANOYL-NBD-D-ERYTHRO-SPHINGOSINE (C6 1 * 100 µG
UOM: 1 * 100 µG
Image Unavailable-CAYM22532-5

N-heptadecanoyl-D-erythro-Sphingosine 1 * 5 mg

Catalog Number: (CAYM22532-5)
Supplier: Cayman Chemical
Description: N-heptadecanoyl-D-erythro-Sphingosine 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM22687-5

N-(2'-(R,S)-hydroxystearoyl)-D-erythro-Sphingosine 1 * 5 mg

Catalog Number: (CAYM22687-5)
Supplier: Cayman Chemical
Description: N-(2'-(R,S)-hydroxystearoyl)-D-erythro-Sphingosine 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10007903-500

D-erythro-Sphingosine C-20 1 * 500 µG

Catalog Number: (CAYM10007903-500)
Supplier: Cayman Chemical
Description: D-erythro-Sphingosine C-20 1 * 500 µG
UOM: 1 * 500 µG
Image Unavailable-CAYM22516-25

N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine 1 * 25 mg

Catalog Number: (CAYM22516-25)
Supplier: Cayman Chemical
Description: N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine 1 * 25 mg
UOM: 1 * 25 mg
Image Unavailable-CAYM10007903-5

D-ERYTHRO-SPHINGOSINE C-20 1 * 5 mg

Catalog Number: (CAYM10007903-5)
Supplier: Cayman Chemical
Description: D-ERYTHRO-SPHINGOSINE C-20 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10007901-5

D-erythro-Sphingosine C-15 1 * 5 mg

Catalog Number: (CAYM10007901-5)
Supplier: Cayman Chemical
Description: D-erythro-Sphingosine C-15 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10007907-10

D-ERYTHRO-SPHINGOSINE C-18 1 * 10 mg

Catalog Number: (CAYM10007907-10)
Supplier: Cayman Chemical
Description: D-ERYTHRO-SPHINGOSINE C-18 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-CAYM10007903-1

D-ERYTHRO-SPHINGOSINE C-20 1 * 1 mg

Catalog Number: (CAYM10007903-1)
Supplier: Cayman Chemical
Description: D-ERYTHRO-SPHINGOSINE C-20 1 * 1 mg
UOM: 1 * 1 mg
Image Unavailable-CAYM10007907-50

D-ERYTHRO-SPHINGOSINE C-18 1 * 50 mg

Catalog Number: (CAYM10007907-50)
Supplier: Cayman Chemical
Description: D-ERYTHRO-SPHINGOSINE C-18 1 * 50 mg
UOM: 1 * 50 mg
Image Unavailable-CAYM22516-1

N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine 1 * 1 mg

Catalog Number: (CAYM22516-1)
Supplier: Cayman Chemical
Description: N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine 1 * 1 mg
UOM: 1 * 1 mg
Image Unavailable-CAYM22688-5

N--hydroxytriacontanoyl-D-erythro-Sphingosine 1 * 5 mg

Catalog Number: (CAYM22688-5)
Supplier: Cayman Chemical
Description: N--hydroxytriacontanoyl-D-erythro-Sphingosine 1 * 5 mg
UOM: 1 * 5 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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