You Searched For: N-Succinimidyl+7-Hydroxycoumarin-3-carboxylate


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Supplier: Apollo Scientific
Description: 6-Hydroxycoumarin 97%

Supplier: Thermo Fisher Scientific
Description: 7-Hydroxycoumarin ≥98%
Supplier: Apollo Scientific
Description: 6-Ethyl-4-hydroxycoumarin 95%

Supplier: AAT BIOQUEST
Description: Carboxyfluorescein (commonly called FAM) and its amine-reactive succinimidyl esters are favored over FITC in bioconjugations.

Catalog Number: (573114-100)
Supplier: Merck Millipore (Calbiochem‎)
Description: Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.
Reacts with primary amines and sulfhydryl groups.
UOM: 1 * 100 mg

Supplier: Thermo Fisher Scientific
Description: Appearance: Off-white to light yellow Crystalline powder
Supplier: AAT BIOQUEST
Description: The acridinium NHS ester can be used to label proteins and nucleic acids.

Supplier: AAT BIOQUEST
Description: SMCC is a non-cleavable and membrane permeable crosslinker with a spacer arm of 8.3 Å. It contains an amine-reactive succinimidyl ester (SE) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7 to 9 to form stable amide bonds. Maleimides react with sulfhydryl groups at pH 6.5 to 7.5 to form stable thioether bonds. The SE group of SMCC is reacted with lysine residues on the carrier protein, converting them to reactive maleimides. SMCC is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.

Catalog Number: (PIERA35394)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
UOM: 1 * 10 mg


Catalog Number: (PIER22360)
Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
UOM: 1 * 50 mg

Supplier: Thermo Fisher Scientific
Description: Appearance: White Crystalline powder
Supplier: Apollo Scientific
Description: 4-(Chloromethyl)-7-hydroxy-2H-chromen-2-one

Catalog Number: (AATB552)
Supplier: AAT BIOQUEST
Description: 7-Hydroxycoumarin-4-acetic acid is used for labeling peptides and proteins to give blue fluorescence.
UOM: 1 * 100 mg


Supplier: Roth Carl
Description: 7-Hydroxycoumarin

Catalog Number: (8.14971.0005)
Supplier: Merck
Description: Di(N-succinimidyl) carbonate for synthesis, Sigma-Aldrich®
UOM: 1 * 5 g

MSDS


Catalog Number: (85969-1G)
Supplier: Merck
Description: Methoxypolyethylene glycol 5000 propionic acid N-succinimidyl ester
UOM: 1 * 1 g


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
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