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Image Unavailable-BOSSBS-0409R-CY5.5

Anti-LEP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-0409R-CY5.5)
Supplier: Bioss
Description: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0108R-CY3

Anti-LEP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-0108R-CY3)
Supplier: Bioss
Description: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7533R-CY5

Anti-LPIN1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-7533R-CY5)
Supplier: Bioss
Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7533R-A555

Anti-LPIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-7533R-A555)
Supplier: Bioss
Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7533R-A680

Anti-LPIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-7533R-A680)
Supplier: Bioss
Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterised by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13721R

Anti-CDHF14 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13721R)
Supplier: Bioss
Description: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0409R-CY7

Anti-LEP Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0409R-CY7)
Supplier: Bioss
Description: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0961R-CY7

Anti-LEPR Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0961R-CY7)
Supplier: Bioss
Description: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0108R-CY5

Anti-LEP Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-0108R-CY5)
Supplier: Bioss
Description: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
UOM: 1 * 100 µl
Product Image-112-4278

Nitrile gloves, Microflex® 93-853

Supplier: Ansell
Description: These disposable gloves feature an advanced proprietary nitrile formulation which delivers an increased tactile sensitivity, reliable durability and up to three times the puncture resistance of latex or vinyl disposable gloves.

Product Image-SAMPM1010B-250

X-ray and metal detectable sampling spatulas, PP, blue

Supplier: Sampling Systems
Description: The X-ray and metal detectable sampling spatula are ideal for use in food and pharmaceutical production and quality control work. The spatulas are made from a special grade of PP that can be detected. The bright blue colour also means that they can be easily seen if left in the powder in line with HACCP guidelines.

Product Image-112-1195

Cleanroom Cut-Resistant Glove Liners

Supplier: WELLS LAMONT
Description: Great for use as a cut-resistant cleanroom glove liner.

Product Image-ABEB37530/41

ESD occupational shoes, clogs, Original plus, 37530

Supplier: Abeba
Description: ESD clog made from preforated leather with a foldable, adjustable heel strap and a PU sole with cross/circle profile (resistant to fuels and animal fats).

Image Unavailable-BOSSBS-0961R-A680

Anti-Leptin Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-0961R-A680)
Supplier: Bioss
Description: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0109R-A555

Anti-LEPR Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-0109R-A555)
Supplier: Bioss
Description: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0109R-CY5.5

Anti-LEPR Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-0109R-CY5.5)
Supplier: Bioss
Description: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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