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PD 174265 1 * 500 µG

Catalog Number: (CAYM17649-500)
Supplier: Cayman Chemical
Description: PD 174265 1 * 500 µG
UOM: 1 * 500 µG
Image Unavailable-CAYM13034-10

PD 0325901 1 * 10 mg

Catalog Number: (CAYM13034-10)
Supplier: Cayman Chemical
Description: PD 0325901 1 * 10 mg
UOM: 1 * 10 mg

MSDS


Image Unavailable-CAYM10010518-50

PD 146176 1 * 50 mg

Catalog Number: (CAYM10010518-50)
Supplier: Cayman Chemical
Description: PD 146176 1 * 50 mg
UOM: 1 * 50 mg
Image Unavailable-NOVUNBP1-77276

PD-1 ANTIBODY 1 * 100 µG

Catalog Number: (NOVUNBP1-77276)
Supplier: Novus Biologicals
Description: PD-1 ANTIBODY 1 * 100 µG
UOM: 1 * 100 µG
Product Image-70-9985-U100

Anti-PDCD1 Armenian Hamster Monoclonal Antibody [clone: J43]

Catalog Number: (70-9985-U100)
Supplier: Tonbo Biosciences
Description: The J43.1 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein which can co-regulate T cell antigen receptor signaling and therefore modulate T cell activation. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells. PD-1 is a member of a family of receptors including CD28 and CTLA-4 (CD152), which interact with “B7” ligands to provide a balance of co-stimulatory /co-inhibitory signaling important in T cell activation, tolerance, and autoimmunity.
UOM: 1 * 100 µG
Image Unavailable-PRSI76-975

Anti-Pdcd1 Hamster Monoclonal Antibody [clone: J43.1]

Catalog Number: (PRSI76-975)
Supplier: ProSci Inc.
Description: The J43.1 monoclonal antibody specifically reacts with mouse CD279, also known as PD-1 (programmed death-1), a 50 to 55 kDa glycoprotein of the Ig superfamily. The PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-H2) are members of the B7 family. Pd-1 contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) and influences the peripheral tolerances and autoimmune diseases in mice. PD-1 is transiently expressed on CD4/CD8 thymocytes, it is upregulated in apoptotic cells, and it is expressed by activated myeloid and T and B cells. The binding of PD-1 to its ligands is blocked by the J43 antibody, which also enhances contact hypersensitivity and exacerbates acute Graft-versus-host disease, Experimental autoimmune encephalomyelitis and NOD diabetes. PD-1 seems to downregulate the immune response, as the development of splenomegaly and breakdown of peripheral tolerance in PD-1 deficient mice suggests.
UOM: 1 * 0,1 mg
Image Unavailable-PRSI76-976

Anti-Pdcd1 Hamster Monoclonal Antibody [clone: J43.1]

Catalog Number: (PRSI76-976)
Supplier: ProSci Inc.
Description: The J43.1 monoclonal antibody specifically reacts with mouse CD279, also known as PD-1 (programmed death-1), a 50 to 55 kDa glycoprotein of the Ig superfamily. The PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-H2) are members of the B7 family. Pd-1 contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) and influences the peripheral tolerances and autoimmune diseases in mice. PD-1 is transiently expressed on CD4/CD8 thymocytes, it is upregulated in apoptotic cells, and it is expressed by activated myeloid and T and B cells. The binding of PD-1 to its ligands is blocked by the J43 antibody, which also enhances contact hypersensitivity and exacerbates acute Graft-versus-host disease, Experimental autoimmune encephalomyelitis and NOD diabetes. PD-1 seems to downregulate the immune response, as the development of splenomegaly and breakdown of peripheral tolerance in PD-1 deficient mice suggests.
UOM: 1 * 0,1 mg
Product Image-85038.180

VWR® ARISTAR®, ICP Multi-Element Solution According USP232 Parental dose 6 Elements 100 mg/L in 15% Hydrochloric Acid

Catalog Number: (85038.180)
Supplier: VWR Chemicals
Description: Six elements: 100 mg/L each of Ir; Pt; Os; Rh; Pd; Ru in HCl 15%.
UOM: 1 * 100 mL

MSDS Certificates


Image Unavailable-VWRI510-827

KIT DISPLAY TFT PP AP PD CIRC 1 * 1 items

Catalog Number: (VWRI510-827)
Supplier: VWR Collection
Description: KIT DISPLAY TFT PP AP PD CIRC 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-PRSI92-496

Mouse recombinant PDCD1

Catalog Number: (PRSI92-496)
Supplier: ProSci Inc.
Description: Programmed Death-1 (PD-1), firstly cloned from mouse T cell hybridoma 2B4.11, is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and acts as an important immunosuppressive molecule. The cytoplamsic tail of PD-1 contains two structural motifs, an immunoreceptor tyrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM) formed by two tyrosine residues which make the difference in PD-1 signal mediating. Mouse PD-1 is expressed in thymus and shares about 69% aa sequence identity with human PD-1. Recently, programmed death-1 (PD-1) with its ligands, programmed death ligand B7H1 (PD-L1) and B7DC (PD-L2), was found to regulate T-cell activation and tolerance, upon ligand binding, inhibiting T-cell effector functions in an antigen-specific manner. PD-1 gene knocked out mice would induce some autoimmune diseases, which suggests that PD-1 acts as a co-inhibitory molecule actively participating in maintaining peripheral tolerance. Thus, PD-1 may be a useful target for the immunologic therapy of carcinoma,infection,autoimmune diseases as well as organ transplantation.
UOM: 1 * 50 µG
Image Unavailable-ABCAAB120568-10

PD 168077 MALEATE 1 * 10 mg

Catalog Number: (ABCAAB120568-10)
Supplier: Abcam
Description: PD 168077 MALEATE 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-APOSOR54811-1G

Brettphos Pd G4 1g pack 1 * 1 g

Catalog Number: (APOSOR54811-1G)
Supplier: Apollo Scientific
Description: Brettphos Pd G4 1g pack 1 * 1 g
UOM: 1 * 1 g

New Product


Image Unavailable-ABCAAB120611-10

PD 168568 DIHYDROCHLORIDE 1 * 10 mg

Catalog Number: (ABCAAB120611-10)
Supplier: Abcam
Description: PD 168568 DIHYDROCHLORIDE 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-PERCN9300138

Palladium standard solution, 1,000 mg/L Pd in 10% hydrochloric acid (from (NH4)2PdCl4) standard for AAS and ICP

Catalog Number: (PERCN9300138)
Supplier: PerkinElmer
Description: Palladium Standard, 1000 mg/L, Palladium, Matrix: 10% HCl, Application: ICP standards
UOM: 1 * 1 items
Image Unavailable-ABCAAB285412-1

A PD-L1 binding peptide 1 * 1 mg

Catalog Number: (ABCAAB285412-1)
Supplier: Abcam
Description: A PD-L1 binding peptide 1 * 1 mg
UOM: 1 * 1 mg
Image Unavailable-APOSIN10425-1G

DavePhos-Pd-G3 1g pack 1 * 1 g

Catalog Number: (APOSIN10425-1G)
Supplier: Apollo Scientific
Description: DavePhos-Pd-G3 1g pack 1 * 1 g
UOM: 1 * 1 g

New Product


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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