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Anti-CD3e/CD4/CD8a Monoclonal Antibody (PE-Cy7®, PE, FITC) [clone: 145-2C11, RM4-5, 53-6.7]

Catalog Number: (91-0000-U100)
Supplier: Tonbo Biosciences
Description: The Mouse T Lymphocyte Subset backbone panel consists of 3 anti-mouse antibodies, each conjugated to a different fluorochrome. This panel can serve as a backbone for identifying major T cell subsets, and leaves room for additional drop-in markers, if desired. An APC version of this panel is available, where the anti-CD8a antibody is conjugated to APC. Hosts: Armenian Hamster, Rat
UOM: 1 * 100 µG
Image Unavailable-60-1276-U025

Anti-Ly-6G Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7) [clone: 1A8]

Supplier: Tonbo Biosciences
Description: The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

Image Unavailable-91-0100-T100

Anti-CD4, CD19, CD20, CD27, CD38, CD45 Mouse Monoclonal Antibody (PerCP-Cy5.5®, PE, redFluor® 710, PE-Cy7®, APC, violetFluor® 450) [clone: OKT4, SJ25C1, 2H7, O323, HIT2, HI30]

Supplier: Tonbo Biosciences
Description: The Human Basic B Lymphocyte backbone panel is a six-color combination of anti-human antibodies. This panel can serve as a backbone to identify the various B lymphocyte subsets, including naive, memory and plasma cells. This panel configuration leaves room for GFP or additional drop-in markers, if desired. Violet laser (405 nm) required for detection of CD45 violetFluoTM 450.

Product Image-60-0453-U100

Anti-CD45.1 Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: A20]

Supplier: Tonbo Biosciences
Description: The A20 antibody reacts with mouse CD 45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

Image Unavailable-60-0564-T100

Anti-CD56 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: MY31]

Supplier: Tonbo Biosciences
Description: The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.

Product Image-60-0108-T500

Anti-CD10 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: SN5c]

Supplier: Tonbo Biosciences
Description: The SN5c antibody is specific for human CD10, a 100 kDa type II transmembrane protein also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA). In normal cells, it is expressed on early B and T lymphoid precursors, neutrophils and on various epithelia. CD10 is also expressed on several lymphoma cells including Burkitt�s, acute lymphoblastic, and follicular germinal center lymphomas. CD10 functions as an endopeptidase and is involved in B cell development, as well as a mediator of neutrophil inflammatory responses.

Product Image-60-7311-U100

Anti-IFNG Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: XMG1.2]

Supplier: Tonbo Biosciences
Description: The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells, which allow the cytokine to modulate innate immunity, when secreted by NK and NKT cells, and to function in supporting adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs).

Product Image-60-0903-U100

Anti-Thy1.2 Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: 30-H12]

Supplier: Tonbo Biosciences
Description: The 30-H12 antibody reacts with mouse CD90.2 (Thy1.2). CD90.2 is a strain-specific allelic form of the GPI-linked membrane associated protein CD90 and is involved in adhesion and signal transduction. CD90.2 is expressed on thymocytes, mature T cells and neurons in mouse strains that express the CD90.2 allele (BALB/c, CBA, C3H, C57BL/6, SJL and others). 30-H12 does not react with the CD90.1 allele expressed in mouse strains such as PL and AKR.

Image Unavailable-BOSSBS-4008R-CY7

Anti-ATG4C Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-4008R-CY7)
Supplier: Bioss
Description: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3873R-CY7

Anti-ATG4A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3873R-CY7)
Supplier: Bioss
Description: ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4009R-CY7

Anti-ATG4D Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-4009R-CY7)
Supplier: Bioss
Description: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
UOM: 1 * 100 µl
Product Image-60-0454-U025

Anti-CD45.2 Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: 104]

Supplier: Tonbo Biosciences
Description: The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. 

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Anti-ATG3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-5204R-CY7)
Supplier: Bioss
Description: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
UOM: 1 * 100 µl
Product Image-60-0193-U025

Anti-CD19 Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: 1D3]

Supplier: Tonbo Biosciences
Description: The 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

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Anti-IL2RA Mouse Monoclonal Antibody [clone: BC96] PE (Phycoerythrin)/Cy7®

Catalog Number: (ABCAAB134479-50)
Supplier: Abcam
Description: N/A
UOM: 1 * 50 Tests
Product Image-60-1271-U100

Anti-IL7R Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: A7R34]

Supplier: Tonbo Biosciences
Description: The A7R34 antibody is specific for mouse CD127, a 60 to 90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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