Catalog Number:
(ENZOADI905745100)
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Supplier:
ENZO LIFE SCIENCES
Description:
The opioid receptors δ, κ, and μ are members of the seven-transmembrane domain-containing receptor family of G-protein coupled receptors. δ- and μ-receptors serve as functional receptors for endogenous enkephalin and β-endorphin peptide ligands, respectively. δ-opioid receptors are highly expressed in the olfactory bulb, neocortex, caudate putamen and nucleus accumbens, with peripheral expression in the gastro-intestinal tract and vas deferens. δ-receptors inhibit neurotransmitter release resulting in a variety of biological effects including analgesia, motor integration, gastro-intestinal motility, olfaction, respiration, and memory. Neural μ-receptor expression is prominent in the caudate putamen, neocortex, thalamus, nucleus accumbens, hippocampus, and amygdala, as well as in peripheral nervous tissues in the gut. Named for its pharmacological mediation of analgesia by morphine, the μ receptor typically functions as a depressant in physiological processes including respiration, cardiovascular function, gastrointestinal motility, and thermoregulation.
UOM:
1 * 100 µG
