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Image Unavailable-BOSSBS-11970R-CY7

Anti-SIX3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11970R-CY7)
Supplier: Bioss
Description: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain. Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, and is maintained in the eye throughout the entire period of fetal development. At 20 weeks of gestation, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer. Six3 maps to human chromosome 2p16-p21, between genetic markers D2S119 and D2S288. The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region.
UOM: 1 * 100 µl
Image Unavailable-BNC880031-500

Anti-MUC5AC Mouse Monoclonal Antibody (CF488A) [clone: 45M1]

Supplier: Biotium
Description: This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Image Unavailable-BNC400031-100

Anti-MUC5AC Mouse Monoclonal Antibody (CF640R) [clone: 45M1]

Supplier: Biotium
Description: This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Product Image-ERGODSVSIGN10SDBDE

Signs, COVID-19 VIRUS social distancing and safety signage - face mask required

Supplier: ERGOMAT
Description: In this very complicated period of operation, we have organized an efficient and quick solution for floor and/or wall marking signage that is in line with the distance rules and recommendations to be observed.

Product Image-ERGODSVSIGN15SDANL

Signs, COVID-19 VIRUS social distancing and safety signage - keep safe distance

Supplier: ERGOMAT
Description: In this very complicated period of operation, we have organized an efficient and quick solution for floor and/or wall marking signage that is in line with the distance rules and recommendations to be observed.

Image Unavailable-BOSSBS-6864R-A750

Anti-NALP12 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-6864R-A750)
Supplier: Bioss
Description: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6864R-A488

Anti-NLRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6864R-A488)
Supplier: Bioss
Description: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6864R-A647

Anti-NLRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-6864R-A647)
Supplier: Bioss
Description: May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11970R

Anti-SIX3 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-11970R)
Supplier: Bioss
Description: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six3 is required for the specification and proliferation of the eye field in vertebrates and may be involved in some developmental disorders of the brain. Expression of Six3 is detected in human embryos as early as five to seven weeks of gestation, and is maintained in the eye throughout the entire period of fetal development. At 20 weeks of gestation, expression of Six3 in the human retina has been observed in ganglion cells and in cells of the inner nuclear layer. Six3 maps to human chromosome 2p16-p21, between genetic markers D2S119 and D2S288. The map position of human Six3 overlaps the positions of two dominant disorders (holoprosencephaly type 2 and Malattia leventinese) with ocular phenotypes that have been assigned to this chromosomal region.
UOM: 1 * 100 µl
Product Image-620-2017

VWR® Traceable®, Water/Shockproof Thermometers

Catalog Number: (620-2017)
Supplier: VWR Collection
Description: These thermometers for wet areas can be used for the monitoring of Liquids, air/gas, or semi-solids in freezers, water baths, outdoor tanks, incubators and refrigerators. At the touch of a button, the memory recalls highest and Lowest temperature readings over any time period. Reading updates every second. Unit is engineered to be shockproof in drop tests up to 1,5 metres.
UOM: 1 * 1 items

Certificates


Image Unavailable-SHBTPB-500-03

Human Recombinant Human Hsc Expansion PB (from E. coli)

Catalog Number: (SHBTPB-500-03)
Supplier: Shenandoah Biotechnology
Description: Cytokines for expansion and cell culture of human hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterised by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of TPO, SCF, and FLT-3 Ligand for short time periods allows CD34+ cells to proliferate without decreasing CD34 expression, thus retaining their stem cell properties. The combination of these cytokines allows for the <i>ex vivo</i> expansion of the most immature hematopoietic stem cells in cord blood or bone marrow preparations, but can be supplemented with other cytokines to promote specific lineages. For example, GM-CSF and/or G-CSF can be added to promote monocytes and granulocytes while EPO can be added to promote erthroid cells.
UOM: 1 * 1 KIT

New Product


Image Unavailable-PRSI33-045

Anti-PER2 Rabbit Polyclonal Antibody

Catalog Number: (PRSI33-045)
Supplier: ProSci Inc.
Description: The Period family of proteins are negative regulators of the circadian clock. The CLOCK-BMAL1 heterodimer is an activator of circadian gene transcription. PER2 (Period circadian protein homolog 2), a member of the Period family of proteins, binds to CLOCK and inhibits its transcriptional activity.
UOM: 1 * 100 µG

New Product


Product Image-ERGOSTRPCORONA1MDE

Signs, COVID-19 VIRUS social distancing and safety signage - please keep safe distance

Supplier: ERGOMAT
Description: In this very complicated period of operation, we have organized an efficient and quick solution for floor and/or wall marking signage that is in line with the distance rules and recommendations to be observed.

Image Unavailable-BOSSBS-2001R-A647

Anti-H1N1 Hemagglutinin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-2001R-A647)
Supplier: Bioss
Description: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability.Influenza A Virus [A/California/04/2009(H1N1)]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2001R-A350

Anti-H1N1 Hemagglutinin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2001R-A350)
Supplier: Bioss
Description: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability.Influenza A Virus [A/California/04/2009(H1N1)]
UOM: 1 * 100 µl
Product Image-AXYGTR8300

Axygen® Storage boxes

Supplier: Corning
Description: These storage boxes are the ideal solution to store samples over an extended period of time. Engineered to simplify sample identity as its polypropylene structure is meant to last.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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