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Product Image-70034.

Fluorescent nerve terminal probes and stains

Supplier: Biotium
Description: Nerve terminal probes are a series of fluorescent cationic styryl dyes developed to follow synaptic activity. These dyes have a lipophilic tail at one end and a hydrophilic cationically charged head group at the other end. The dyes vary in the number of carbons in the lipophilic tail (m) and the number of double bonds linking the two aromatic rings in the dye (n). AM dyes are similar to FM dyes, but contain an additional formaldehyde-fixable amino group in the cationic head.

Image Unavailable-ENZOADIVAMPS005D

Anti-SAP97 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
Description: Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP.

Image Unavailable-MFLX95954-07

Masterflex® Transfer Tubing, Terminator®, Avantor®

Supplier: Avantor Fluid Handling
Description: Superior abrasion resistance at high pressure.

Product Image-BOSSBS-12942R

Anti-CSK Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12942R)
Supplier: Bioss
Description: All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLSE5280010

Human recombinant DPP9

Catalog Number: (ENZOBMLSE5280010)
Supplier: ENZO LIFE SCIENCES
Description: Produced in insect cells. Active recombinant human DPP9 with an N-terminal purification tag.
UOM: 1 * 10 µG
Image Unavailable-BOSSBS-10377R-A680

Anti-Galectin-3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-10377R-A680)
Supplier: Bioss
Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterised by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9174R-CY5.5

Anti-TRIM3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-9174R-CY5.5)
Supplier: Bioss
Description: Tripartite motif-containing protein 3 (TRIM3), also known as RING finger protein 22 (RNF22), RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), is a 744 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments, TRIM3 has been shown to interact with å-actinin-4 and myosin V, two proteins associated with the actin cytoskeleton. Specifically, å-actinin-4 interacts with the RBCC domain of TRIM3, and the C-terminal tail of Myosin V interacts with with the unique C-terminal ∫-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10377R-CY7

Anti-GAL3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-10377R-CY7)
Supplier: Bioss
Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10377R-CY5

Anti-GAL3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-10377R-CY5)
Supplier: Bioss
Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11339R-CY3

Anti-CLSTN2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11339R-CY3)
Supplier: Bioss
Description: Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
UOM: 1 * 100 µl
Product Image-AGLS240101

InterPlay adenoviral TAP system

Catalog Number: (AGLS240101)
Supplier: AGILENT
Description: The InterPlay Mammalian TAP system allows you to recover interacting proteins from mammalian cells.
UOM: 1 * 60 µG
Image Unavailable-BOSSBS-13260R-CY5

Anti-GABT3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13260R-CY5)
Supplier: Bioss
Description: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10377R-A350

Anti-GAL3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-10377R-A350)
Supplier: Bioss
Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10377R-A555

Anti-GAL3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-10377R-A555)
Supplier: Bioss
Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
UOM: 1 * 100 µl
Image Unavailable-ENZOENZ42733

Fluorescein-12-ddUTP dideoxynucleotide pack for 3’-oligonucleotide labeling

Catalog Number: (ENZOENZ42733)
Supplier: ENZO LIFE SCIENCES
Description: The procedure for labeling of DNA probes with a polynucleotide 'tail' containing hapten-labeled nucleotides was developed by Enzo. In such terminal labeling reactions, terminal transferase catalyzes the addition of nucleotides to any 3'-OH terminus in a template independent manner. This rapid and convenient nonradioactive labeling procedure is free of any sequence bias that is normally observed in random priming or nick translation reactions.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-6446R-A680

Anti-Lin-28 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-6446R-A680)
Supplier: Bioss
Description: Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognises the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognises and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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