You Searched For: Potassium+3-carboxy-5-nitrophenyltrifluoroborate

Supplier: Apollo Scientific

Description: 1-(2-Aminoethyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid, 1-BOC protected

Catalog Number: (BOSSBS-11987R-A555)

Supplier: Bioss

Description: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11987R-CY3)

Supplier: Bioss

Description: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11987R-FITC)

Supplier: Bioss

Description: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.

UOM: 1 * 100 µl

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Supplier: VWR Chemicals

Description: , anhydrous ≥98% for synthesis

MSDS Certificates

Catalog Number: (85733.290)

Supplier: VWR Chemicals

Description: Carrez II solution potassium hexacyanoferrate(II) 0.25 mol/l in aqueous solution

UOM: 1 * 1 L

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Supplier: Thermo Fisher Scientific

Description: Potassium wolframate ≥99.5% (metals basis)

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Supplier: VWR Chemicals

Description: Potassium hexacyanoferrate(II) trihydrate ≥99.0%, AnalaR NORMAPUR® analytical reagent

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Supplier: Apollo Scientific

Description: Amino-PEG4-acid

Supplier: Thermo Fisher Scientific

Description: Potassium thiocyanate 99+% for analysis

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Supplier: Avantor

Description: This reagent is satisfactory for use as a pH standard. For use as an acidimetric standard, this material should be lightly crushed and dried for 2 hours at 120 °C to remove any absorbed moisture.

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Catalog Number: (458222B)

Supplier: VWR Chemicals

Description: K in H₂O tr.HNO₃.

UOM: 1 * 100 mL

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Catalog Number: (6748-20)

Supplier: MACRON AVANTOR BRAND

Description: Potassium hydrogen carbonate 99.7-100.5%, granular, AR® ACS, Macron Fine Chemicals™

UOM: 1 * 12 kg

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Catalog Number: (USBIC7947-98C)

Supplier: US Biological

Description: Anti-CTDSP1 Goat polyclonal antibody

UOM: 1 * 100 µG

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Supplier: VWR Chemicals

Description: Ready to use test solutions (TS).

MSDS Certificates

Catalog Number: (BOSSBS-4250R-FITC)

Supplier: Bioss

Description: The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

UOM: 1 * 100 µl

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