Print…

You Searched For: Renin+Substrate+1


21 638  results were found

Refine Results Sort by
SearchResultCount:"21638"

Sort Results

List View Easy View

Rate These Search Results

Image Unavailable-BOSSBS-5935R-CY5.5

Anti-KLHL7 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-5935R-CY5.5)
Supplier: Bioss
Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5104R-A555

Anti-HEXIM2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-5104R-A555)
Supplier: Bioss
Description: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLPR1040500

Calcineurin inhibitory peptide

Catalog Number: (ENZOBMLPR1040500)
Supplier: ENZO LIFE SCIENCES
Description: Sequence is calcineurin (CaN) autoinhibitory domain (rat brain CaN aa 457-482). It inhibits calcineurin with an IC50 of 10 µM using [32P]myosin light chain as substrate. Inhibits Mn²⁺-stimulated calcineurin activity but has no effect on Ni²⁺-stimulated activity. Ki=4,4 µM with radiolabeled [Ala97]-RII (81-99) peptide as the phosphatase substrate.
UOM: 1 * 0,5 mg
Image Unavailable-BOSSBS-5935R-CY3

Anti-KLHL7 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5935R-CY3)
Supplier: Bioss
Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1135R-CY7

Anti-SRC Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1135R-CY7)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1135R-FITC

Anti-SRC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1135R-FITC)
Supplier: Bioss
Description: c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine kinase in human embryonic kidney 293T cells. We have identified 10 known substrates and interactors of c-Src and Src family kinases along with 26 novel substrates. We have experimentally validated 4 of the novel proteins (NICE-4, RNA binding motif 10, FUSE-binding protein 1 and TRK-fused gene) as direct substrates of c-Src using in vitro kinase assays and cotransfection experiments. Significantly, using a c-Src specific inhibitor, we were also able to implicate 3 novel substrates (RNA binding motif 10, EWS1 and Bcl-2 associated transcription factor) in PDGF signaling. Finally, to identify the exact tyrosine residues that are phosphorylated by c-Src on the novel c-Src substrates, we designed custom peptide microarrays containing all possible tyrosine-containing peptides (312 unique peptides) and their mutant counterparts containing a Tyr -->Phe substitution from 14 of the identified substrates. Using this platform, we identified 34 peptides that are phosphorylated by c-Src. We have demonstrated that SILAC-based quantitative proteomics approach is suitable for identification of substrates of nonreceptor tyrosine kinases and can be coupled with peptide microarrays for high-throughput identification of substrate phosphopeptides.
UOM: 1 * 100 µl
Image Unavailable-APOSPC7306-100MG

2-Deoxy-2-fluoro-D-glucose

Supplier: Apollo Scientific
Description: A substrate of hexokinase isozymes.

Image Unavailable-ENZOALX480019M010

6-(Benzyloxy)-7H-purin-2-amine ≥98% (by TLC)

Catalog Number: (ENZOALX480019M010)
Supplier: ENZO LIFE SCIENCES
Description: DNA alkyltransferase substrate and inhibitor
UOM: 1 * 10 mg
Image Unavailable-ENZOBMLP1110001

[Ser25]-Protein kinase C (19-31)

Catalog Number: (ENZOBMLP1110001)
Supplier: ENZO LIFE SCIENCES
Description: PKC substrate
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLP2560500

Histone H3 dimethyl lysine-4 peptide

Catalog Number: (ENZOBMLP2560500)
Supplier: ENZO LIFE SCIENCES
Description: Demethylase substrate
UOM: 1 * 0,5 mg
Image Unavailable-ENZOBMLP1350025

H-Arg-AMC·2HCl

Catalog Number: (ENZOBMLP1350025)
Supplier: ENZO LIFE SCIENCES
Description: Substrate for cathepsin H and aminopeptidases
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLP2130005

MeOSuc-AAPV-pNA

Catalog Number: (ENZOBMLP2130005)
Supplier: ENZO LIFE SCIENCES
Description: Substrate for neutrophil elastase and neutrophil proteinase 3
UOM: 1 * 5 mg
Image Unavailable-R0392

IPTG (isopropyl-β-D-thiogalactopyranoside) enzyme substrate dioxane-free

Supplier: Thermo Fisher Scientific
Description: The IPTG (isopropyl-beta-D-thiogalactopyranoside) is a highly stable synthetic analog of lactose

Image Unavailable-ENZOBMLP3230001

[pTyr992] EGF receptor (988-998)

Catalog Number: (ENZOBMLP3230001)
Supplier: ENZO LIFE SCIENCES
Description: PTP1B substrate
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLP2760001

Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

Catalog Number: (ENZOBMLP2760001)
Supplier: ENZO LIFE SCIENCES
Description: MMP substrate
UOM: 1 * 1 mg
Image Unavailable-ENZOBMLAK3060001

MMP Fluorometric drug discovery kits, RED and GREEN

Supplier: ENZO LIFE SCIENCES
Description: The matrix metalloproteinase (MMP) RED and GREEN Drug Discovery Kits are complete assay systems designed to screen MMP inhibitors, using long-wavelength quenched fluorogenic substrates OmniMMP™ RED or Fluorogenic Substrate (GREEN). The assays are performed in a convenient 96-well microplate format, with the compound NNGH also included as a prototypic control inhibitor.

Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
433 - 448 of 21 638
no targeter for Bottom