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Image Unavailable-BOSSBS-5935R-A680

Anti-KLHL7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5935R-A680)
Supplier: Bioss
Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5104R-A488

Anti-HEXIM2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5104R-A488)
Supplier: Bioss
Description: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9515R-CY7

Anti-CTH Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-9515R-CY7)
Supplier: Bioss
Description: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3695R-CY7

Anti-KPNB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3695R-CY7)
Supplier: Bioss
Description: NTF97 is involved in nuclear protein import, either by associating itself with an adapter protein (for example, importin-alpha subunit which binds to nuclear localization signals (NLS) in cargo substrates), or by acting autonomously as a nuclear transport receptor (serves as NLS receptor, docking of the importin/substrate complex to the nuclear pore complex).
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLLA0041000

Leukotriene A4 methyl ester ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Substrate for LTA₄ hydrolase and LTC₄ synthase.

Image Unavailable-APOSBIN0365-1680G

Naphthol AS-TR phosphate disodium salt

Supplier: Apollo Scientific
Description: Substrate for the histochemical demonstration of acid and alkaline phosphatase

Image Unavailable-BOSSBS-3090R-A647

Anti-CBL Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3090R-A647)
Supplier: Bioss
Description: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3090R-CY5

Anti-CBL Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3090R-CY5)
Supplier: Bioss
Description: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5147R-CY5

Anti-CBL Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5147R-CY5)
Supplier: Bioss
Description: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]
UOM: 1 * 100 µl
Image Unavailable-APOSBIM1097-10G

4-Methylumbelliferyl-β-D-glucopyranoside

Supplier: Apollo Scientific
Description: Fluorescent substrate for b-D-galactosidase.

Image Unavailable-APOSBIM1096-100MG

4-Methylumbelliferyl-alpha-D-glucopyranoside

Supplier: Apollo Scientific
Description: Fluorescent substrate for a-D-glucoside.

Image Unavailable-USBIP3350-125KU

Peroxidase, Horseradish, RZ3 (POD, HRP, HRPO)

Supplier: US Biological
Description: Horseradish Peroxidase (HRP) is a hemoprotein catalysing the oxidation by hydrogen peroxide of a number of substrates such as ascorbate, ferrocyanide, cytochrome C and the leuko form of many dyes.

New Product

Image Unavailable-ENZOALX850216KI01

Caspase-3 fluorometric assay kit

Catalog Number: (ENZOALX850216KI01)
Supplier: ENZO LIFE SCIENCES
Description: Based on the detection of AFC (7-amino-4-trifluoromethyl coumarin) after cleavage from the labelled substrate DEVD-AFC.
UOM: 1 * 25 Tests
Image Unavailable-MLDVR8160

IMAP kinase, phosphatase, and phosphodiesterase assays, molecular devices

Catalog Number: (MLDVR8160)
Supplier: Molecular Devices
Description: IMAP® technology provides a homogeneous assay applicable to a wide variety of kinases without regard for substrate peptide sequence.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-3695R-A350

Anti-KPNB1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-3695R-A350)
Supplier: Bioss
Description: NTF97 is involved in nuclear protein import, either by associating itself with an adapter protein (for example, importin-alpha subunit which binds to nuclear localization signals (NLS) in cargo substrates), or by acting autonomously as a nuclear transport receptor (serves as NLS receptor, docking of the importin/substrate complex to the nuclear pore complex).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3359R-A680

Anti-MARCKS Ser162 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3359R-A680)
Supplier: Bioss
Description: MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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