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Product Image-442-0480

VWR®, Magnetic stirring bars, double ended

Supplier: VWR Collection
Description: <B>PTFE</B> covered, strong Alnico V magnetic core. Smooth surface. Very good centring, small footprint and high turbulence even at low speeds. Disc diameter 20 mm, rod diameter 8 mm.

Product Image-SCOT1170682

Accessories for connection system GLS 80

Catalog Number: (SCOT1170682)
Supplier: DWK Life Sciences
Description: Screw cap, PBT, GL 18, red
UOM: 1 * 2 items
Product Image-228-1331

Pump tubing, Tygon® S3™ E-LFL

Catalog Number: (228-1331)
Supplier: Saint Gobain Life Sciences
Description: Non DEHP and phthalate-free tubing.
UOM: 1 * 12 items
Image Unavailable-BOSSBS-8415R

Anti-HEATR7B2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-8415R)
Supplier: Bioss
Description: HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR7B2 (HEAT repeat-containing protein 7B2) is a 1,585 amino acid protein that contains fifteen HEAT repeats. Existing as two alternatively spliced isoforms, the gene encoding HEATR7B2 maps to human chromosome 5p13.1 and mouse chromosome 15 A1. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Cockayne syndrome is associated with chromosome 5 through the ERCC8 gene and familial adenomatous polyposis via the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM: 1 * 100 µl
Product Image-763-0145

Poster - Human Skeleton, Rear View

Catalog Number: (763-0145)
Supplier: 3B Scientific
Description: The human skeleton anatomy poster is delivered with wooden rods for easy display.
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-217-9206

Screw caps for square bottles, DURAN®

Supplier: DWK Life Sciences
Description: PP, red or blue.

Image Unavailable-BOSSBS-1938R

Anti-ZW10 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-1938R)
Supplier: Bioss
Description: The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. It is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, whereas another ZW10 partner, Zwint-1, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1. Zwint-1 is critical for recruiting ZW10 to unattached kinetochores. Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores. Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived "stop anaphase" inhibitor.
UOM: 1 * 100 µl
Product Image-BOCH17023

Triple clamps

Supplier: BOCHEM
Description: Holder for Schott laboratory flasks for the alternating removal of vessel and lid.

Image Unavailable-BOSSBS-1938R-A750

Anti-ZW10 Peptide Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-1938R-A750)
Supplier: Bioss
Description: The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. It is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, whereas another ZW10 partner, Zwint-1, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1. Zwint-1 is critical for recruiting ZW10 to unattached kinetochores. Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores. Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyse generation of the mitotic checkpoint-derived 'stop anaphase' inhibitor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1938R-A647

Anti-ZW10 peptide Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1938R-A647)
Supplier: Bioss
Description: The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. It is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, whereas another ZW10 partner, Zwint-1, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1. Zwint-1 is critical for recruiting ZW10 to unattached kinetochores. Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores. Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived "stop anaphase" inhibitor.
UOM: 1 * 100 µl
Image Unavailable-1.01369.0100

Media additives and supplements

Supplier: Merck
Description: Neutral red indicator, Application: Additive, Glass bottle

MSDS

Product Image-HACHE21M001

Reference electrodes, Radiometer Analytical

Supplier: Hach
Description: Radiometer Analytical reference electrodes are available with a variety of reference systems and liquid junctions.

Product Image-DIDAPOD060080

High quality prismatic optical bench

Catalog Number: (DIDAPOD060080)
Supplier: DIDALAB
Description: Triangular, cast aluminium optical bench
UOM: 1 * 1 items
Product Image-763-0159

Poster - Respiratory Organs

Catalog Number: (763-0159)
Supplier: 3B Scientific
Description: Wall poster, supplied with wooden rods for easy display in any classroom.
UOM: 1 * 1 items

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-ACRO304550250

Bromophenol red, pure

Supplier: Thermo Fisher Scientific
Description: Bromophenol red, pure

MSDS Certificates

Image Unavailable-BOSSBS-0548R-HRP

Anti-MERTK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0548R-HRP)
Supplier: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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