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Supplier: ENZO LIFE SCIENCES

Description: Gentamicin sulphate

Supplier: BIOWEST

Description: Gentamycin sulphate acts against Gram-negative, Gram-positive bacteria and mycoplasma.

Supplier: Thermo Fisher Scientific

Description: Gentamicin sulphate

Supplier: BIOWEST

Description: Gentamicin sulfate acts against gram-negative, gram-positive bacteria and mycoplasma.

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Supplier: Apollo Scientific

Description: An aminoglycoside antibiotic.

Catalog Number: (PROOICRS0319)

Supplier: LGC Standards PROMOCHEM

Description: Gentamicin sulphate

UOM: 1 * 100 mg

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Supplier: BIOWEST

Description: Gentamicin sulfate acts against gram-negative, gram-positive bacteria and mycoplasma.

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Supplier: PanReac AppliChem

Description: Gentamicin sulphate

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Catalog Number: (MOLEM17289509)

Supplier: Molekula

Description: Gentamicin sulphate

UOM: 1 * 25 g

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Catalog Number: (MOLE10336465-5G)

Supplier: Molekula

Description: Gentamicin sulphate

UOM: 1 * 5 g

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Supplier: AAT BIOQUEST

Description: Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. Fluorophore-tagged drugs, such as gentamicin-Texas Red (GTTR) conjugates, have been used to identify drug trafficking routes across the BLB and into hair cells, and specifically in the cochlea - the sensory organ responsible for hearing. Identifying the mechanisms involved in the intracochlear trafficking of ototoxic drugs to hair cells is of fundamental as well as clinical importance. Texas Red-gentamicin conjugate (GTTR) provides researchers a valuable tool to study the cellular uptake, kinetics and distribution of gentamicin through fluorescence techniques, such as fluorescence microscopy, fluorescence correlation spectroscopy, single molecule spectroscopy. The TR fluorophore can be conveniently excited from 500-600 nm, with an emission maximum centered around 610 nm. Acute nephrotoxicity and permanent ototoxicity are serious side-effects that increase patient morbidity, or induce permanent auditory and vestibular deficits. Several approaches have been used to study the intracellular mechanisms induced by ototoxic drugs. However, ototoxic drugs must first cross the blood-labyrinth barrier (BLB) before entering sensory hair cells to exert their cytotoxic effect that leads to hearing loss and deafness. The BLB is similar to the blood-brain barrier (BBB), and is composed of tight junction-coupled endothelial and epithelial barrier layers that transport nutrients and ions from one side of the barrier to the other.

Supplier: MP Biomedicals

Description: Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five equivalents of sulfuric acid per mole of gentamicin base. Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria. Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. Gentamicin sulfate inhibits bacterial protein biosynthesis by binding to the 30S subunit of the ribosome.

Supplier: MP Biomedicals

Description: Gentamicin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by gram-negative organisms.

Supplier: Corning

Description: An antibiotic agent, gentamicin inhibits protein synthesis by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site

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Catalog Number: (ICNA0916762J8)

Supplier: MP Biomedicals

Description: Gentamicin sulphate 50 mg/ml, Reagent Grade

UOM: 1 * 100 mL

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Catalog Number: (MDTC30-005-CR)

Supplier: Corning

Description: Gentamicin works as an antimicrobial agent by binding to the 30S ribosomal subunit of certain bacteria.

UOM: 1 * 10 items

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