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Image Unavailable-BOSSBS-10098R-A750

Anti-S100A6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukaemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.
Catalog Number: BOSSBS-10098R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10098R-A350

Anti-HDAC5 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.
Catalog Number: BOSSBS-10098R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-6675R-A350

Anti-KCNN4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Catalog Number: BOSSBS-6675R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13306R-HRP

Anti-GUCA1A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.
Catalog Number: BOSSBS-13306R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13308R-A647

Anti-GUCA1C Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating proteins (GCAP). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina. GCAP3 (Guanylyl cyclase-activating protein 3), also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin. Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), which increases cGMP concentration. Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure. There are two isoforms of GCAP3 that are produced as a result of alternative splicing events.
Catalog Number: BOSSBS-13308R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13308R-HRP

Anti-GUCA1C Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating proteins (GCAP). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina. GCAP3 (Guanylyl cyclase-activating protein 3), also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin. Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), which increases cGMP concentration. Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure. There are two isoforms of GCAP3 that are produced as a result of alternative splicing events.
Catalog Number: BOSSBS-13308R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-APOSBII0421-10MG

Ionomycin free acid

Description: Potent and selective calcium ionophore.
Catalog Number: APOSBII0421-10MG
UOM: 1 * 10 mg
Supplier: Apollo Scientific
Image Unavailable-50011.

FLUO-3 pentapotassium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Description: Fluo-3, pentapotassium is membrane-impermeant, but can be loaded into cells via microinjection or scrape loading.
Catalog Number: 50011.
UOM: 1 * 1 mg
Supplier: Biotium
Image Unavailable-ABCAAB259950-1ML

Anti-Calcium-independent Phospholipase A2/PLA2G6 Rabbit Monoclonal Antibody [clone: EPR23994-103]

Description: Anti-Calcium-independent Phospholipase A2/PLA2G6 Rabbit Monoclonal Antibody [clone: EPR23994-103]
Catalog Number: ABCAAB259950-1ML
UOM: 1 * 1 mL
Supplier: Abcam

New Product


Image Unavailable-BOSSBS-9046R-FITC

Anti-TRPM3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number: BOSSBS-9046R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9046R-CY5

Anti-TRPM3 Rabbit Polyclonal Antibody (Cy5®)

Description: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number: BOSSBS-9046R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-9046R-A647

Anti-TRPM3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Catalog Number: BOSSBS-9046R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-1562R-A750

Anti-Annexin A1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Catalog Number: BOSSBS-1562R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10156R-A555

Anti-NOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.
Catalog Number: BOSSBS-10156R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-10156R-A750

Anti-NOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.
Catalog Number: BOSSBS-10156R-A750
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11980R-A647

Anti-CABP4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.
Catalog Number: BOSSBS-11980R-A647
UOM: 1 * 100 µl
Supplier: Bioss
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