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Catalog Number: (BOSSBS-15371R-CY7)
Supplier: Bioss
Description: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
UOM: 1 * 100 µl


Supplier: Thermo Fisher Scientific
Description: When used with conventional HPLC systems and appropriate switching valves, these columns provide effective removal of contaminants, such as proteins, from samples and fast, effective clean-up and concentration of target compounds.

Supplier: EPPENDORF
Description: Eppendorf Maxitips are designed for large volume liquid handling, offering high precision and compatibility with Eppendorf pipetting systems. Ideal for diverse lab applications, they ensure accuracy and ease of use, enhancing workflow efficiency.

Environmentally Preferable

Catalog Number: (BURK2507-2000)
Supplier: BURKLE
Description: Empty bottle for 600 ml contents, leakproof due to valve and dust protection cap. Instructions printed on (in German), made of transparent PE.
UOM: 1 * 1 items


Catalog Number: (300-0407)
Supplier: BURKLE
Description: The food pressure sprayer has a transparent viewing window to make it easy to read the fill level. A rubber-coated ring stand ensures that the sprayer can be set down securely. A built-in safety valve protects against overpressure (maximum 3 bar).
UOM: 1 * 1 items


Supplier: BRANSON
Description: M and MH Series ultrasonic baths are known for offering a high level of precision and reliability.

Catalog Number: (ILMV2019C-02)
Supplier: Welch by Gardner Denver
Description: Pumps are constructed with PTFE heads, perfluoroelastomer valves and a PTFE coated molded diaphragm. Includes intake/exhaust hose barbs. DRYFAST® models include tunable vacuum control.
UOM: 1 * 1 items


Supplier: DWK Life Sciences
Description: Made of PTFE.

Catalog Number: (BOSSBS-15371R-A647)
Supplier: Bioss
Description: Atypical chemokine receptor that controls chemokine levels and localisation via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalising receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
UOM: 1 * 100 µl


Catalog Number: (WITG5.661.250)
Supplier: witeg Labortechnik
Description: Borosilicate glass 3.3. This vacuum desiccator has 10.5 litre capacity.
UOM: 1 * 1 items


Supplier: SciLabware
Description: Fully interchangeable PTFE keys for Pyrex® stopcocks.

Supplier: IKA
Description: The HBC circulating baths have a high-quality stainless steel bath, an extended temperature range for tempering fluids in open and covered water baths up to 200/250 °C. The LED/ graphic TFT Display illustrates all relevant process parameters. The large surface of the radiator allows for an optimum heat exchange and a smooth warming of the medium. Units feature push and turn buttons for intuitive menu navigation. All models conform to the highest safety classification III (FL) for use with flammable liquids according to DIN 12876. HBC immersion circulators ensure short heating up times and have a temperature stability of ±0,01 /0,02 K ( basic/control model). The units have an integrated cooling coil, adjustable safety circuit and a front drain valve for safe emptying. To drain the system, a separate valve helps to avoid direct contact with fluid.

Supplier: 3M
Description: The 3M™ Aura™ Health Care Particulate Respirators provide effective respiratory protection for use in medical environments where health care workers will be exposed to airborne dust particles, non-volatile liquid particles and bioaerosols. These respirators limit the transmission of infective agents from staff to patients and are suitable for use during surgical procedures and certain other medical procedures. These products also offer resistance to penetration of splashes of liquid.

Supplier: DWK Life Sciences
Description: SBW glass, clear.

Supplier: RSG
Description: Bunsen burner made of stainless steel.

Supplier: Brand
Description: Dessicators with polycarbonate lid, PP base and desiccant tray. Venting stopper with non-return valve in lid. Seal between lid and base: polychlorobutadiene rubber (CK) O-ring, compressed by vacuum.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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