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Image Unavailable-BOSSBS-11873R-A488

Anti-LINGO4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Lingo-4 is a 593 amino acid single-pass type I membrane protein that contains eleven LRR (leucine-rich) repeats, one Ig-like C2-type (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. The gene that encodes Lingo-4 consists of approximately 5,891 bases and maps to human chromosome 1q21.3. Comprising nearly 8% of the human genome, chromosome 1 spans 260 million base pairs, contains over 3,000 genes and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Catalog Number: BOSSBS-11873R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11873R-A647

Anti-LINGO4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Lingo-4 is a 593 amino acid single-pass type I membrane protein that contains eleven LRR (leucine-rich) repeats, one Ig-like C2-type (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. The gene that encodes Lingo-4 consists of approximately 5,891 bases and maps to human chromosome 1q21.3. Comprising nearly 8% of the human genome, chromosome 1 spans 260 million base pairs, contains over 3,000 genes and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Catalog Number: BOSSBS-11873R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11638R-A647

Anti-LZIC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: LZIC is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: BOSSBS-11638R-A647
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5371R-CY5

Anti-PMVK Rabbit Polyclonal Antibody (Cy5®)

Description: PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
Catalog Number: BOSSBS-5371R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-5371R-A488

Anti-PMVK Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
Catalog Number: BOSSBS-5371R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12382R-HRP

Anti-EYA3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome.
Catalog Number: BOSSBS-12382R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-15075R-FITC

Anti-C1orf69 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Catalog Number: BOSSBS-15075R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-15075R-HRP

Anti-C1orf69 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Catalog Number: BOSSBS-15075R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13171R-CY5

Anti-FHAD1 Rabbit Polyclonal Antibody (Cy5®)

Description: The FHAD1 gene encodes a 1,420 amino acid protein and maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: BOSSBS-13171R-CY5
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11841R-FITC

Anti-FNBP1L Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Catalog Number: BOSSBS-11841R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11841R-A488

Anti-FNBP1L Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Catalog Number: BOSSBS-11841R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-11841R-A350

Anti-FNBP1L Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Catalog Number: BOSSBS-11841R-A350
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13515R-A488

Anti-ADGRA2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Catalog Number: BOSSBS-13515R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13515R-CY7

Anti-ADGRA2 Rabbit Polyclonal Antibody (Cy7®)

Description: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Catalog Number: BOSSBS-13515R-CY7
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-13515R-A680

Anti-GPR124 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Catalog Number: BOSSBS-13515R-A680
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-12418R-FITC

Anti-BAMBI Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
Catalog Number: BOSSBS-12418R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
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