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Image Unavailable-BOSSBS-15076R-CY3

Anti-C1orf77 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-15076R-CY3)
Supplier: Bioss
Description: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-HT40432-1L

Papanicolaou's solution EA 65, Sigma-Aldrich®

Catalog Number: (HT40432-1L)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Papanicolaou stain imparts a characteristic range of coloration to exfoliative cells of vaginal, cervical, prostatic and other body secretions, allowing critical examination of nuclei and cytoplasmic components.
UOM: 1 * 1 L
Image Unavailable-BOSSBS-11620R-HRP

Anti-RGS21 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11620R-HRP)
Supplier: Bioss
Description: The regulators of G protein signaling (RGS) proteins inhibit heterotrimeric G protein signaling. RGS proteins work by functioning as GTPase-activators (which increase the GTPase activity of G protein a-subunits) thereby driving G proteins into their inactive GDP-bound form. RGS21 (regulator of G-protein signaling 21) is a 152 amino acid protein that is ubiquitously expressed and contains one RGS domain. The gene encoding RGS21 maps to human chromosome 1q31.2 and mouse chromosome 1 F. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
UOM: 1 * 100 µl
Product Image-VART6106301404

Professional Batteries

Supplier: VARTA GERAETEBATTERIE
Description: Battery, Lithium batteries, Voltage: 1,5 V, Ø×H: 10,5×44,5 mm

Product Image-241-0349

Clamps, universal, slewable

Catalog Number: (241-0349)
Supplier: USBECK Laborgeräte
Description: Universal clamp made of powder-coated zinc die-cast.With cork lined jaws.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-1437R-HRP

Anti-MRP5/ABCC5 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Catalog Number: (BOSSBS-1437R-HRP)
Supplier: Bioss
Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9181R-A750

Anti-Repetin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-9181R-A750)
Supplier: Bioss
Description: Repetin is a 784 amino acid secreted protein that belongs to the S100-fused protein family. Repetin is an extracellular epidermal matrix protein that is expressed in the epidermis and at high levels in eccrine sweat glands, the inner sheaths of hair roots and the filiform papilli of the tongue. A multifunctional epidermal matrix protein, repetin is involved in the cornified cell envelope formation. Containing two EF-hand domains, repetin?s recombinant N-terminal domain binds calcium reversibly. Repetin and trichohyalin may compensate for absent loricrin. The repetin gene contains three exons, two introns and spans at least 5.6 kb. The repetin gene is conserved in cow, mouse and rat, and maps to human chromosome 1q21.3.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13171R-A680

Anti-FHAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-13171R-A680)
Supplier: Bioss
Description: The FHAD1 gene encodes a 1,420 amino acid protein and maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15474R-CY3

Anti-HHAT Rabbit Polyclonal Antibody (Cy3)

Catalog Number: (BOSSBS-15474R-CY3)
Supplier: Bioss
Description: HHAT is a 493 amino acid multi-pass membrane protein that localises to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyse the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localise to chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15474R-CY5

Anti-HHAT Rabbit Polyclonal Antibody (Cy5)

Catalog Number: (BOSSBS-15474R-CY5)
Supplier: Bioss
Description: HHAT is a 493 amino acid multi-pass membrane protein that localises to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyse the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localise to chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15474R-CY7

Anti-HHAT Rabbit Polyclonal Antibody (Cy7)

Catalog Number: (BOSSBS-15474R-CY7)
Supplier: Bioss
Description: HHAT is a 493 amino acid multi-pass membrane protein that localises to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyse the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localise to chromosome 1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13379R-CY7

Anti-COLGALT2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13379R-CY7)
Supplier: Bioss
Description: GLT25D2 is a 626 amino acid protein that localizes to endoplasmic reticulum lumen and belongs to the glycosyltransferase 25 family. Possessing beta-galactosyltransferase activity, GLT25D2 transports beta-galactose to hydroxylysine residues on collagen but lacks glucosyltransferase activity. GLT25D2 is expressed in skeletal muscle and brain, and is encoded by a gene located on human chromosome 1q25.3, a region associated with the hereditary prostate cancer (HPC1) locus. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13379R-CY5

Anti-COLGALT2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-13379R-CY5)
Supplier: Bioss
Description: GLT25D2 is a 626 amino acid protein that localizes to endoplasmic reticulum lumen and belongs to the glycosyltransferase 25 family. Possessing beta-galactosyltransferase activity, GLT25D2 transports beta-galactose to hydroxylysine residues on collagen but lacks glucosyltransferase activity. GLT25D2 is expressed in skeletal muscle and brain, and is encoded by a gene located on human chromosome 1q25.3, a region associated with the hereditary prostate cancer (HPC1) locus. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3953R-A647

Anti-COX1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3953R-A647)
Supplier: Bioss
Description: Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3953R-FITC

Anti-COX1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-3953R-FITC)
Supplier: Bioss
Description: Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13515R-A647

Anti-ADGRA2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-13515R-A647)
Supplier: Bioss
Description: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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