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Image Unavailable-BOSSBS-11752R-CY3

Anti-REEP1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11752R-CY3)
Supplier: Bioss
Description: Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.
UOM: 1 * 100 µl
Product Image-30-1271-U025

Anti-IL7R Rat Monoclonal Antibody (Biotin) [clone: A7R34]

Supplier: Tonbo Biosciences
Description: The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.

Product Image-75-1271-U100

Anti-IL7R Rat Monoclonal Antibody (violetFluor® 450) [clone: A7R34]

Supplier: Tonbo Biosciences
Description: The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.

Product Image-MILFHAWG047S6

S-Pak® Membrane Filters

Supplier: Merck
Description: S-Pak™ hydrophilic sterile membranes are protected with a blue sheet of paper that keeps the membrane encountering with the film by ensuring maximum productivity and efficiency. This protective sheet prevents the migration of any adhesive.

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Image Unavailable-BOSSBS-6520R-CY5

Anti-CKAP4 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-6520R-CY5)
Supplier: Bioss
Description: High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2545R-A350

Anti-IL2RG Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2545R-A350)
Supplier: Bioss
Description: Interleukin 2 (IL2) receptor gamma chain (IL5212R gamma) is a cell surface glycoprotein expressed by a variety of leukocytes including T cells, B cells, NK cells, monocytes, macrophages, and neutrophils. IL2R gamma is also known as CD132, common cytokine receptor gamma chain, and gamma c. IL2R gamma forms complexes with other cell surface proteins including CD25 (IL2R alpha), CD122 (IL2R beta), CD124 (IL4R alpha), CD127 (IL7R), and others. IL2R gamma complexed with other cell surface proteins forms receptors for the cytokines IL2, IL4, IL7, IL9, and IL15. Acting through the IL2R gamma containing complexes, these cytokines regulate lymphocyte development and activation. Chemical cross linking experiments reveal that IL2R gamma is able to bind cytokines only when complexed with these other cell surface proteins. In addition to interacting with other cell surface glycoproteins, IL2R gamma associates with several cytoplasmic tyrosine kinases including JAK3 (Janus Kinase 3), JAK1, Syc, and Lyc. Cytokine binding to the IL2R gamma containing receptor complexes activates these tyrosine kinases. Once activated, these tyrosine kinases phosphorylate their associated receptors, creating docking sites for signaling molecules such as PI 3 kinase. The activated tyrosine kinases also phosphorylate downstream regulators including STAT3 (Signal Transducer and Activator of Transcription 3), STAT5, and STAT6. The various cytokines that bind to IL2R gamma containing receptor complexes exert their effects through unique repertoires of cytoplasmic signaling molecules. IL2, IL7, and IL9 exert their effects through cascades, which activate STAT3 and STAT5, while IL4 activates STAT6. IL2 and IL15 exert their effects through cascades, which activate the MAP kinase cascade. IL7 exerts its effects through a cascade that results in VDJ immunoglobulin gene rearrangement.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1309R-CY5.5

Anti-SDC1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1309R-CY5.5)
Supplier: Bioss
Description: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1309R-CY7

Anti-SDC1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-1309R-CY7)
Supplier: Bioss
Description: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
UOM: 1 * 100 µl
Product Image-P5SCX-150A

Avantor® Partisil SCX, HPLC Columns

Supplier: Avantor
Description: Avantor® Partisil® was one of the first commercially available irregular silicas with a large surface area giving it a high loading capacity.

Product Image-554-5674

Avantor® Partisil Avantor® Partisphere, HPLC Columns

Supplier: Avantor
Description: Commercially available spherical silicas and it continues to provide and reproducible, high efficiency separations, Avantor® Partisphere® columns are available in a wide range of surface chemistries including two application specific phases.

Image Unavailable-BOSSBS-0091R-CY7

Anti-MUC16 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-0091R-CY7)
Supplier: Bioss
Description: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3574R-CY7

Anti-ADAM10 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3574R-CY7)
Supplier: Bioss
Description: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3574R-CY5

Anti-ADAM10 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3574R-CY5)
Supplier: Bioss
Description: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3574R-A350

Anti-ADAM10 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-3574R-A350)
Supplier: Bioss
Description: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10031R-HRP

Anti-CSNK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-10031R-HRP)
Supplier: Bioss
Description: Important role in determination of the surface properties of the casein micelles.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7351R-A488

Anti-CD200R1L Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-7351R-A488)
Supplier: Bioss
Description: May be a receptor for the CD200/OX2 cell surface glycoprotein.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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