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Catalog Number: (BOSSBS-2190R-CY5)
Supplier: Bioss
Description: Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Antibody to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.
UOM: 1 * 100 µl


Catalog Number: (171-0553)
Supplier: Merck
Description: Pure and ultra pure water system, UV lamp for Direct Q® 3 UV and Synergy™
UOM: 1 * 1 items


Catalog Number: (PRSI91-832)
Supplier: ProSci Inc.
Description: IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
UOM: 1 * 50 µG


Catalog Number: (PRSI29-327)
Supplier: ProSci Inc.
Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein.
UOM: 1 * 100 µG


Catalog Number: (PRSI26-477)
Supplier: ProSci Inc.
Description: ORAI2 is a multi-pass membrane protein, and it belongs to the Orai family. It is a Ca (2+) release-activated Ca (2+)-like (CRAC-like) channel subunit which mediates Ca (2+) influx and increase in Ca (2+)-selective current by synergy with the Ca (2+) sensor, STIM1.
UOM: 1 * 50 µG


Supplier: SPS
Description: These pouches offer users an effective microbial barrier while guaranteeing the effective flow of the sterilizing agent and a peel-off system which provides aseptic conditions on opening. Through medical paper specially developed to meet the requirements of steam sterilization, these pouches have a 60 g/m² paper surface which is performance-equivalent in terms of resistance and barrier to 70 g/m² paper. Apart from the ecological aspect concerning the volume of waste to be treated, the reinforced 60 g/m² paper, combined with tear-proof 'shatterless' film, offers flexible packaging and easy opening that are incomparable for this type of packaging.

Catalog Number: (PRSI91-779)
Supplier: ProSci Inc.
Description: Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.
UOM: 1 * 50 µG


Catalog Number: (32913-1ML)
Supplier: Merck
Description: T-2-Triol is classified under the trichothecene family of mycotoxins that can adversely affect animal and human health. It is most commonly found in agricultural products.
UOM: 1 * 1 mL


Catalog Number: (PRSI29-061)
Supplier: ProSci Inc.
Description: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
UOM: 1 * 50 µG


Catalog Number: (32541-1ML)
Supplier: Merck
Description: Microcystin is a type of toxin which can adversely affect human health. It is released by cyanobacteria and is commonly found in fresh water sources.
UOM: 1 * 1 mL


Catalog Number: (330902Q)
Supplier: VWR Chemicals
Description: These tablets are prepared according to the formula given in the British Ministry of Health's Memo 139/Foods. One tablet dissolved in 500 ml of glass-distilled water yields quarter strength Ringer's solution.
UOM: 1 * 100 Tablet

Supplier: STEMCELL Technologies
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda <i>et al.</i>). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 T cells (Francisco-Cruz <i>et al.</i>). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton <i>et al.</i>). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. Recombinant human GM-CSF (rhGM-CSF) promotes the production of myeloid cells of the granulocytic (neutrophils, eosinophils and basophils) and monocytic lineages in vivo. It has been tested for mobilization of hematopoietic progenitor cells and for treating chemotherapy-induced neutropenia in patients. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz <i>et al.</i>).

Supplier: STEMCELL Technologies
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda <i>et al.</i>). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz <i>et al.</i>). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton <i>et al.</i>). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz <i>et al.</i>).

Catalog Number: (BE-502)
Supplier: G-Biosciences
Description: Dot blotting is a simple technique to identify a known protein in a biological sample. The ease and simplicity of the technique makes dot blotting an ideal diagnostic tool.
UOM: 1 * 1 KIT


Supplier: Merck
Description: Specially developed screw caps for direct instrument connection of Merck S 40 threaded bottles ensure safe handling of solvents in the lab and protect human health, the environment, as well as solvent quality.
Supplier: 3M
Description: The 3M™ Aura™ Health Care Particulate Respirators provide effective respiratory protection for use in medical environments where health care workers will be exposed to airborne dust particles, non-volatile liquid particles and bioaerosols. These respirators limit the transmission of infective agents from staff to patients and are suitable for use during surgical procedures and certain other medical procedures. These products also offer resistance to penetration of splashes of liquid.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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