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Catalog Number: (BOSSBS-2537R-HRP)
Supplier: Bioss
Description: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
UOM: 1 * 100 µl


Supplier: Sartorius
Description: Filter cartridge, Type: Analytical kit, arium® pro cartridge set for biological, chemical-analytical

Supplier: Sartorius
Description: This mechanical pipette with large display has been designed with comfort in mind. Tacta makes pipetting effortless and safe, while producing accurate and reliable results. The pipette is made from carefully selected materials, with each component designed to meet the highest standards.

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Catalog Number: (BIBBD3/12)
Supplier: SciLabware
Description: PYREX®, borosilicate glass, cylindrical shape.
UOM: 1 * 5 items


Catalog Number: (LOVI411296)
Supplier: Lovibond
Description: Comparator 2000+ is a versatile modular system for testing water.This kit measures chlorine, alkalinity, pH calcium hardness and cyanuric acid.
UOM: 1 * 1 KIT


Supplier: Sartorius
Description: Extension tubing set (4 m) for the Arium® Smart Station is designed to provide uncomplicated extension of the connection between the Arium® Smart Station and the connected water system.

Catalog Number: (SARTFT-3-01304-025)
Supplier: Sartorius
Description: These non woven grades are made of rayon. Ideal for the filtration or prefiltration of viscous solutions containing particles visible with the naked eye.
UOM: 1 * 100 items


Supplier: STERILIN
Description: Square shaped PS weighing boats. Raw material modified to significantly reduce the charge relaxation time in comparison to standard weigh boats. Majority of electrostatic charge dissipates within seconds when earthed on the balance pan.

Catalog Number: (SART4768)
Supplier: Sartorius
Description: Incucyte® Annexin V dye for apoptosis is a specially formulated, highly-selective phosphatidylserine (PS) cyanine fluorescent dye, designed for real-time evaluation of apoptosis in living cultures.
UOM: 1 * 1 Vial

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Catalog Number: (PRSI27-165)
Supplier: ProSci Inc.
Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
UOM: 1 * 50 µG


Catalog Number: (BOHLH998-18)
Supplier: Bohlender
Description: Screw caps made of PP, with handy knurl. Sealing insert made of PTFE with elastic sealing lip and an o-ring for balancing unevenness on the bottle neck.
UOM: 1 * 1 items


Supplier: Industrial Physics
Description: profi LIGNO are moisture meters specifically designed for wood and building materials such as screed or gypsum.

Supplier: Hanna
Description: These technical calibration buffers produced in accordance with ISO 3696/BS3978 standards using high purity salts, deionised water, certified weight-checked balances, and Class A glassware in a temperature controlled environment monitored with certified thermometers.
Catalog Number: (SHBT200-26AF-200UG)
Supplier: Shenandoah Biotechnology
Description: Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.
UOM: 1 * 200 µG


Supplier: Sartorius
Description: These smooth filter papers are made of refined pulp and linters with more than 95% alpha-cellulose content. The ash content of these filter papers is between 0,1 and 0,15%.

Catalog Number: (ROTH5481.1)
Supplier: Roth Carl
Description: These brushes with brush head made of goat head and with white-painted birchwood handle are ideal for dusting weighing boats, scales and weights.
UOM: 1 * 3 items

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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