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Mouse Recombinant IL-31 (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

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Mouse Recombinant FLT-3 Ligand (Animal free) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3).

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N-Methyl-2-pyrrolidone (NMP) ≥99.7%, Biotechnology Grade, Burdick & Jackson™

Supplier: Honeywell Chemicals
Description: N-Methyl-2-pyrrolidone (NMP) ≥99.7%, Biotechnology Grade for biotechnology, Burdick & Jackson™

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Human Recombinant IL-6 (CTGrade GMP) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: IL-21 is a common chain cytokine regulating many cell types of the immune system. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Plays an important role in the development of humoral immunity through its effects on B cell biology including differentiation, affinity maturation, and memory responses.

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Mouse Recombinant Neural SCE PB (from E. coli)

Catalog Number: (SHBTPB-500-18)
Supplier: Shenandoah Biotechnology
Description: IL-2C126S, an immune-regulating cytokine originating from lymphocytes, operates via the IL-2R receptor to trigger the expansion of activated T cells and encourage T cell maturation. IL-2 mediates its action by binding to IL-2 receptors (IL-2R), consisting of either trimeric receptors made of IL-2Rα (CD25), IL-2Rβ (CD122), and IL-2Rγ (γc, CD132) chains or dimeric βγ IL-2Rs.
UOM: 1 * 1 KIT

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Human Recombinant TH17 Cell Polarizing Plus PB (from E. coli)

Catalog Number: (SHBTPB-500-12)
Supplier: Shenandoah Biotechnology
Description: Cytokines for polarizing human T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. An important function of IL-9 producing T cells is fighting inflammation and helminth infections. Th9 cells can be generated from naive CD4+ T cells in culture by culturing them in the presence of IL-4 and TGF-β 1. It also appears that IFNγ and IL-27 can inhibit the generation of Th9 cells.
UOM: 1 * 1 KIT

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Agarose I, powder general purpose reagent, for biotechnology low electroendosmosis (EEO)

Supplier: G-Biosciences
Description: G-Biosciences offers several different biotechnology-grade agarose powders. G-Biosciences' Agarose I has low electroendosmosis (EEO) and high electrophoresis mobility. It is suitable for nucleic acid analytical and preparative electrophoresis, blotting, and protein electrophoresis (i.e. radial immunodiffusion).

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Agarose II, powder, melt_low Biotechnology

Supplier: G-Biosciences
Description: G-Biosciences offers several different biotechnology-grade agarose powders. Agarose II has a low melting and gelling temperature compared to standard agaroses. The low melting temperature allows for the recovery of undamaged nucleic acids below the denaturation temperature. The low gelling temperature ensures that the agarose will be in a liquid state at a temperature range where in-gel manipulations can be performed without prior extraction from the agarose slice.

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Agarose IV, powder, Gel_Highest Strength Biotechnology

Supplier: G-Biosciences
Description: G-Biosciences offers several different biotechnology-grade agarose powders. Agarose IV is a linear polymer with a very high molecular weight, giving gel structures unlike those of traditional agaroses. This characteristic produces a strong intercatenary interaction, yeilding a gel with very high gel strength and higher exclusion limit.

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Mouse Recombinant HSC Expansion PB (from E. coli)

Catalog Number: (SHBTPB-500-04)
Supplier: Shenandoah Biotechnology
Description: Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.
UOM: 1 * 1 KIT

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Horse Recombinant RE VEGF-165 (Animal free) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: FLT-3 Ligand is a growth factor that regulates proliferation of early hematopoietic cells. FLT-3 Ligand binds to cells expressing the tyrosine kinase receptor FLT-3. FLT-3 ligand by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, FLT-3 ligand exerts no activity on mast cells. Multiple isoforms of FLT-3 Ligand have been identified.

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Human Recombinant PDGF-BB (CTGrade GMP) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Epidermal Growth Factor (EGF) exerts its effects by binding to the EGF Receptor, a protein kinase that initiates the intracellular signaling. EGF is widely distributed in tissues like the kidney, cerebrum, prostate, and salivary glands. EGF acts as a potent factor in promoting cell division, and the phosphorylated receptor recruit adapter proteins like GRB2, which then activate complex downstream signaling cascades.

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Human Recombinant GM-CSF (CTGrade GMP) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively.

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Acetonitrile, (dried basis), Biotechnology Grade (max. 10 ppm H₂O), Burdick & Jackson™

Catalog Number: (HONC65739-7L)
Supplier: Honeywell Chemicals
Description: Acetonitrile, (dried basis), Biotechnology Grade (max. 10 ppm H₂O), Burdick & Jackson™
UOM: 1 * 7 L
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Human Recombinant IL-21 (CTGrade GMP) (from E. coli)

Supplier: Shenandoah Biotechnology
Description: PDGF-BB (Platelet-derived growth factor) comprises a family of homo or heterodimeric growth factors, including PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD. Binds to two different transmembrane tyrosine kinase receptors (PDGFR-alpha and PDFGR-beta). Released from degranulating platelets and plays a role in each stage of wound healing. Stimulates mitogenicity and chemotaxis of neutrophils, macrophages, fibroblasts, and smooth muscle cells to the wound site.

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Horse Recombinant RE VEGF-165 (from E. coli)

Supplier: Shenandoah Biotechnology
Description: Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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