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Catalog Number: (BOSSBS-6023R-CY5)
Supplier: Bioss
Description: Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6023R-CY7)
Supplier: Bioss
Description: Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
UOM: 1 * 100 µl


Catalog Number: (PRSI79-740)
Supplier: ProSci Inc.
Description: Nucleoside 2', 3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.
UOM: 1 * 100 µG


Supplier: Honeywell Chemicals
Description: di-Sodium tetraborate decahydrate ≥99.5% ACS, Fluka™
Supplier: MP Biomedicals
Description: Colistin is a polymyxin antibiotic, and is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic.
Supplier: Honeywell Chemicals
Description: di-Sodium tetraborate decahydrate ≥99.5%, Puriss. p.a. ACS, ISO buffer substance, Fluka™
Catalog Number: (AATB17105)
Supplier: AAT BIOQUEST
Description: Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction.
UOM: 1 * 100 µG


Catalog Number: (PRSI25-617)
Supplier: ProSci Inc.
Description: RNA 3-prime-terminal phosphate cyclase catalyzes the ATP-dependent conversion of a 3-prime phosphate to a 2-prime,3-prime-cyclic phosphodiester at the end of RNA.RNA 3-prime-terminal phosphate cyclase (RPC; EC 6.5.1.4) catalyzes the ATP-dependent conversion of a 3-prime phosphate to a 2-prime,3-prime-cyclic phosphodiester at the end of RNA (Genschik et al., 1997 [PubMed 9184239]).
UOM: 1 * 50 µG


Supplier: MERCK PRODUCTION CHEMICALS
Description: di-Sodium tetraborate decahydrate, EMPROVE® ESSENTIAL Ph. Eur., BP, JP, NF, SAFC®
Catalog Number: (PIER26101)
Supplier: Thermo Fisher Scientific
Description: Pierce™ Traut's Reagent (2-Iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition)
UOM: 1 * 500 mg

Supplier: Honeywell Chemicals
Description: pH Buffer solution, Borate, pH value: 9,00, ±0.02, Reference temperature: 20 °C, Fluka™, 6×1 L
Catalog Number: (USBI033501)
Supplier: US Biological
Description: Anti-CD38 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl


Supplier: Honeywell Chemicals
Description: Buffers with fungicide (except pH 10,012)

Catalog Number: (USBI150787)
Supplier: US Biological
Description: Anti-PDE4D3 Goat Polyclonal Antibody
UOM: 1 * 100 µG


Catalog Number: (BOSSBS-3964R-CY3)
Supplier: Bioss
Description: PKA (or cAPK) is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, C beta, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states. C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3964R-A680)
Supplier: Bioss
Description: PKA (or cAPK) is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, C beta, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states. C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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