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Tyrphostin A23 ≥99% (by TLC)

Catalog Number: (ENZOBMLEI1910010)
Supplier: ENZO LIFE SCIENCES
Description: A potent inhibitor of EGF receptor kinase activity (IC50=35 µM).
UOM: 1 * 10 mg
Image Unavailable-J60308.MA

Tyrphostin A23 99%

Catalog Number: (J60308.MA)
Supplier: Thermo Fisher Scientific
Description: Tyrphostin A23 99%
UOM: 1 * 10 mg

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Image Unavailable-APOSOR32985-1G

Tyrphostin 1 95%

Supplier: Apollo Scientific
Description: Tyrphostin 1 95%

Product Image-ENZOALX270141M025

Tyrphostin AG 527 ≥98% (by HPLC)

Catalog Number: (ENZOALX270141M025)
Supplier: ENZO LIFE SCIENCES
Description: Tyrphostin AG 527 ≥98% (by HPLC)
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLEI2290002

Tyrphostin B7 ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Member of the tyrphostin family of tyrosine kinase inhibitors. Selective inhibitor of the PDGF receptor kinase (IC50=20µM) vs. the EGF receptor kinase (IC50=820µM). Inhibits PDGF-induced mitogenesis in human bone marrow fibroblasts.

Image Unavailable-ENZOBMLEI2150050

Tyrphostin A9 ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Tyrphostin 9 is a selective inhibitor of the PDGF receptor tyrosine kinase (IC50=1.2 µM). It is also a potent (10 nM) uncoupler of oxidative phosphorylation.

Image Unavailable-ENZOBMLEI1900020

Tyrphostin 1 ≥99%

Supplier: ENZO LIFE SCIENCES
Description: An inactive tyrphostin, which may be used as a negative control.

Image Unavailable-ENZOBMLEI1870005

Tyrphostin A25 ≥99%

Catalog Number: (ENZOBMLEI1870005)
Supplier: ENZO LIFE SCIENCES
Description: A potent inhibitor of EGF receptor kinase activity (IC50=3 µM).
UOM: 1 * 5 mg
Image Unavailable-APOSBISN0202-5MG

Tyrphostin AG-126

Catalog Number: (APOSBISN0202-5MG)
Supplier: Apollo Scientific
Description: MAPK/ERK Signalling Pathway
UOM: 1 * 5 mg
Image Unavailable-ENZOALX270217M005

Tyrphostin AG 1024 ≥98% (by HPLC and UV method)

Supplier: ENZO LIFE SCIENCES
Description: Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.

Image Unavailable-ENZOBMLEI2720050

Tyrphostin AG 490 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

Image Unavailable-ENZOALX270035M005

Tyrphostin AG 1295 ≥98%

Catalog Number: (ENZOALX270035M005)
Supplier: ENZO LIFE SCIENCES
Description: Selective inhibitor of tyrosine kinase in platelet-derived growth factor (PDGF) receptor.
UOM: 1 * 5 mg
Image Unavailable-APOSBIT1101-100MG

Tyrphostin AG 1478 free base 99+%

Supplier: Apollo Scientific
Description: Very potent EGF receptor kinase (tyrosine kinase) inhibitor (IC50 = 3 nM). Very weak on PDGF receptor and HER2-NEU kinases (IC50 >100 uM). Eur. J. Biochem. 225: 1047-1053 (1994).

Image Unavailable-ENZOALX270036M005

Tyrphostin AG 1478 ≥98% (by HPLC)

Catalog Number: (ENZOALX270036M005)
Supplier: ENZO LIFE SCIENCES
Description: EGFR inhibitor
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLEI1890005

Tyrphostin AG 183 ≥99%

Catalog Number: (ENZOBMLEI1890005)
Supplier: ENZO LIFE SCIENCES
Description: A potent inhibitor of EGF receptor kinase activity (IC50=0.8 µM). Inhibition is mixed competitive with ATP and substrate.
UOM: 1 * 5 mg
Image Unavailable-ENZOBMLEI3030025

Tyrphostin AG-1296 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: A potent inhibitor of PDGF receptor tyrosine kinase (IC50=1 µM). Also inhibits FGF receptor tyrosine kinase and c-kit. Induces apoptosis in a small-cell lung cancer cell line (H526).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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