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Tyrphostin AG-126 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: AG-126 prevents lipopolysaccharide-induced lethal toxicity (septic shock) in mice. Administered at 1.5 mg/mouse, it reduced LPS-induced lethal toxicity from 95% to 10%. AG-126 greatly reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. EGFR, Her-2/neu receptor or PDGF-R are not inhibited at 100 µM. Inhibits tyrosine kinase-dependent B cell receptor signaling.

Image Unavailable-USBI124461

Anti-CCL23 Rabbit Polyclonal Antibody

Catalog Number: (USBI124461)
Supplier: US Biological
Description: Anti-CCL23 Rabbit Polyclonal Antibody
UOM: 1 * 100 µG
Image Unavailable-ENZOBMLPR1130050

4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).

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AG-879 ≥99%

Supplier: ENZO LIFE SCIENCES
Description: NGF receptor inhibitor

Image Unavailable-ENZOBMLEI2520005

RG-13022 ≥98% (by TLC)

Catalog Number: (ENZOBMLEI2520005)
Supplier: ENZO LIFE SCIENCES
Description: RG-13022 is a non-phenolic tyrphostin analog, which inhibits the EGF receptor (IC50=5 µM) and PDGF receptor tyrosine kinases, and is long-acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=1 µM) as well as tumor growth in vivo. It inhibits both EGF- and PDGF-stimulated DNA synthesis in human glioma cell lines. RG-13022 is non-phenolic and therefore possesses less antioxidant activity than other tyrphostins.
UOM: 1 * 5 mg
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AG-494 ≥98% (by TLC)

Catalog Number: (ENZOBMLEI2280010)
Supplier: ENZO LIFE SCIENCES
Description: AG-494 is a member of the tyrphostin family of tyrosine kinase inhibitors and is a potent inhibitor of EGF receptor autophosphorylation (IC50=1.2 µM) and EGF-dependent cell growth (IC50=6 µM). It selectively inhibits HER1 (EGF receptor) vs. HER1-2 receptor autophosphorylation (HER1: IC50=1.1 µM; HER1-2: IC50=45 µM). HER1-2 is a chimeric receptor consisting of the external HER1 domain fused to an internal HER2 domain. Blocks CDK2 activation and causescells to arrest at late G1 and during S phase.
UOM: 1 * 10 mg
Image Unavailable-J65227.MA

Tyrphostin C15

Catalog Number: (J65227.MA)
Supplier: Thermo Fisher Scientific
Description: Tyrphostin C15
UOM: 1 * 10 mg

MSDS


Image Unavailable-J61704.MA

Tyrphostin B46 ≥98%

Catalog Number: (J61704.MA)
Supplier: Thermo Fisher Scientific
Description: Tyrphostin B46 ≥98%
UOM: 1 * 10 mg

MSDS Certificates


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FIXED ANGLE ROTOR A23-6X100 1 * 1 items

Catalog Number: (SORV75003006)
Supplier: Thermo Fisher Scientific
Description: FIXED ANGLE ROTOR A23-6X100 1 * 1 items
UOM: 1 * 1 items
Image Unavailable-BWRLAP0765

Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin i s a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures. 1 * 100 µG

Catalog Number: (BWRLAP0765)
Supplier: Bioworld Technology
Description: Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin i s a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures. 1 * 100 µG
UOM: 1 * 100 µG
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TYRPHOSTIN 47 1 * 5 mg

Catalog Number: (ABCAAB141558-5)
Supplier: Abcam
Description: TYRPHOSTIN 47 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10010315-5

TYRPHOSTIN 51 1 * 5 mg

Catalog Number: (CAYM10010315-5)
Supplier: Cayman Chemical
Description: TYRPHOSTIN 51 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10010315-10

TYRPHOSTIN 51 1 * 10 mg

Catalog Number: (CAYM10010315-10)
Supplier: Cayman Chemical
Description: TYRPHOSTIN 51 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-CAYM10010243-5

TYRPHOSTIN AG-825 1 * 5 mg

Catalog Number: (CAYM10010243-5)
Supplier: Cayman Chemical
Description: TYRPHOSTIN AG-825 1 * 5 mg
UOM: 1 * 5 mg
Image Unavailable-CAYM10010300-10

TYRPHOSTIN 23 1 * 10 mg

Catalog Number: (CAYM10010300-10)
Supplier: Cayman Chemical
Description: TYRPHOSTIN 23 1 * 10 mg
UOM: 1 * 10 mg
Image Unavailable-CAYM10010312-10

TYRPHOSTIN 25 1 * 10 mg

Catalog Number: (CAYM10010312-10)
Supplier: Cayman Chemical
Description: TYRPHOSTIN 25 1 * 10 mg
UOM: 1 * 10 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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