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Anti-C4A Mouse Monoclonal Antibody (CF594) [clone: TDM16]

Supplier: Biotium
Description: This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Image Unavailable-BNC040205-100

Anti-C4A Mouse Monoclonal Antibody (CF405S) [clone: C4D205]

Supplier: Biotium
Description: This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Image Unavailable-BNCB0205-100

Anti-C4A Mouse Monoclonal Antibody (Biotin) [clone: C4D205]

Supplier: Biotium
Description: This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Image Unavailable-BNC471232-500

Anti-C4A Mouse Monoclonal Antibody (CF647) [clone: TDM16]

Supplier: Biotium
Description: This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Image Unavailable-BNUM0204-50

Anti-C4A Mouse Monoclonal Antibody (Purified, BSA-free) [clone: C4D204]

Catalog Number: (BNUM0204-50)
Supplier: Biotium
Description: This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
UOM: 1 * 50 µl
Image Unavailable-APOSOR6435-250MG

1-Benzyl-4-isocyanato-5-methyl-1H-1,2,3-triazole 95%

Catalog Number: (APOSOR6435-250MG)
Supplier: Apollo Scientific
Description: When melted, may contain small amount of sediment.
UOM: 1 * 250 mg
Product Image-BOHLR1123-04

b.safe Desktop Distributors

Supplier: Bohlender
Description: Central waste collection from several HPLC systems. Capillaries and hoses are connected without kinks using the b.safe Fittings and b.safe Hose connectors included in the scope of delivery. The liquid solvent waste flows off directly and residue-free via the vertical hole inside the Desktop Distributor.

Product Image-BOHLM255-30

Control Waste Cap DLC, b.safe

Supplier: Bohlender
Description: To avoid spill over of canisters through the connection of a b.safe Control Waste Cap to a b.safe Display for electronic level control.

Image Unavailable-BOSSBS-1698R-CY5.5

Anti-ox-LDL Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1698R-CY5.5)
Supplier: Bioss
Description: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
UOM: 1 * 100 µl
Image Unavailable-APOSOR22981-1G

4-Isocyanato-5-methyl-3-phenylisoxazole

Catalog Number: (APOSOR22981-1G)
Supplier: Apollo Scientific
Description: When melted, may contain small amount of sediment
UOM: 1 * 1 g
Product Image-ACE2131546MVK

Avantor® ACE® C4-300, HPLC Columns, 3 µm

Supplier: Avantor
Description: Avantor® ACE® C4-300 columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Image Unavailable-A13870.30

trans-4-Methoxycinnamic acid 98%

Supplier: Thermo Fisher Scientific
Description: trans-4-Methoxycinnamic acid 98%

MSDS Certificates

Product Image-SCOI285418547

Thermostatic baths for viscometers, CT 72

Supplier: SI Analytics
Description: The CT 72 thermostatic baths are designed for determining viscosity of newtonian liquids in glass capillary viscometers with the display of the momentary and the set temperature through VF display.

Product Image-620-2459

ASTM-Like precision thermometers, ACCU-SAFE

Supplier: Ludwig Schneider GmbH & CO. KG
Description: Precision thermometer, ideal to measure precisely and reliably without mercury from the very start.

Product Image-ACE-116-7502

Avantor® ACE® AQ, HPLC Columns, 3 µm

Supplier: Avantor
Description: Avantor® ACE® AQ columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Product Image-115-2439

Wipes, pre-saturated, PROSAT®

Catalog Number: (115-2439)
Supplier: CONTEC
Description: The melt blown polypropylene wipes provide a consistent release of solvent to thoroughly remove surface contaminants in critical environments.
UOM: 1 * 1.080 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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