You Searched For: Tyrphostin+B7


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Catalog Number: (ANTIA77732-96)
Supplier: ANTIBODIES.COM
Description: Human B7-H6 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human B7-H6 in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Catalog Number: (PRSI90-371)
Supplier: ProSci Inc.
Description: B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.
UOM: 1 * 100 µG


Catalog Number: (ABNOMAB23523.100)
Supplier: Abnova
Description: Anti-RELA (pSer536) Rabbit Monoclonal Antibody [clone: B7] (FITC)
UOM: 1 * 100 AU


Catalog Number: (ABNOMAB23524.100)
Supplier: Abnova
Description: Anti-RELA (pSer536) Rabbit Monoclonal Antibody [clone: B7] (APC)
UOM: 1 * 100 AU


Catalog Number: (ABNOMAB23522.100)
Supplier: Abnova
Description: Anti-RELA (pSer536) Rabbit Monoclonal Antibody [clone: B7] (PE)
UOM: 1 * 100 AU


Catalog Number: (PRSI54-342)
Supplier: ProSci Inc.
Description: Anti-Drd2 Rabbit Monoclonal Antibody [clone: B7]
UOM: 1 * 100 µG

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Catalog Number: (ORIGCF505477)
Supplier: OriGene
Description: Anti-GADD45G Mouse Monoclonal Antibody [clone: B7]
UOM: 1 * 100 µG


Catalog Number: (PRSI76-954)
Supplier: ProSci Inc.
Description: The TY25 antibody reacts with mouse B7-DC (PD-L2), a 42 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. B7-DC is expressed by macrophages, monocytes, and sub-populations of dendritic cells. B7-DC has similarities with the rest of the B7 family, but it does not bind to CD28/CD152. The receptor for B7-DC is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between B7-DC and its receptor seems to downregulate immune responses. However, B7-DC seems to be a costimulator of T lymphocytes, reacting with a receptor different than PD-1. B7-DC can bind and stimulate dendritic cells. It is also the first B-7 ligand involved in bidirectional communication. The TY25 monoclonal antibody blocks the binding of B7-DC to its receptor (PD-1) and can be used for studying the interaction between the antigen presenting cells and T lymphocytes.
UOM: 1 * 0,1 mg

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Catalog Number: (PRSI90-399)
Supplier: ProSci Inc.
Description: CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be up-regulated through interferon-gamma. B7-1 and B7-2 are both members of the immunoglobulin superfamily. It has been observed that both human and mouse B7-1 and B7-2 can bind to either human or mouse CD28 and CTLA-4, suggesting that there are conserved amino acids which form the B7-1/B7-2/CD28/CTLA-4 critical binding sites.
UOM: 1 * 100 µG


Catalog Number: (ABNOH00029979-M02)
Supplier: Abnova
Description: Anti-UBQLN1 Mouse Monoclonal Antibody [clone: 1C6-B7]
UOM: 1 * 100 µG


Supplier: ANTIBODIES.COM
Description: Recombinant Human B7-H6 (from HEK293 cells)

New Product

Catalog Number: (PRSI90-434)
Supplier: ProSci Inc.
Description: Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
UOM: 1 * 100 µG


Catalog Number: (PRSI90-435)
Supplier: ProSci Inc.
Description: Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
UOM: 1 * 100 µG


Catalog Number: (STMC100-1599)
Supplier: STEMCELL Technologies
Description: Mouse monoclonal antibody against human, rhesus CD80 (B7-1), PE-conjugated.
UOM: 1 * 100 Tests

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Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (STMC100-1600)
Supplier: STEMCELL Technologies
Description: Mouse monoclonal antibody against human, rhesus CD80 (B7-1), APC-conjugated.
UOM: 1 * 100 Tests

New Product

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (ANTIA86658-100)
Supplier: ANTIBODIES.COM
Description: Mouse monoclonal [BB7.1] antibody to HLA B7 for Flow Cytometry with samples derived from Human and Non-Human Primates.
UOM: 1 * 100 µG

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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