You Searched For: VAS-2870


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Supplier: ENZO LIFE SCIENCES
Description: Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).

New Product

Catalog Number: (201901-50G)
Supplier: SIGMA ALDRICH MICROSCOPY
Description: Chrysophenine, Dye content 65 % (Direct Yellow 12)
UOM: 1 * 50 g


Sturdy, high quality, stainless steel FoodScoops

Very stable hand scoop, particularly suited for the food industry. Seamless connection of scoop and hollow handle, therefore without crevices and edges.

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Smooth, highly polished surface

Bürkle
Catalog Number: (481-0872)
Supplier: TUTTNAUER
Description: Stainless steel wire basket, (Ø×H): 357×365 mm, For: 2840 ELV/MLV, 2850 ELV/MLV, 2870 ELV/MLV
UOM: 1 * 1 items


Catalog Number: (USBIF0011-31)
Supplier: US Biological
Description: Anti-Factor Va Sheep Polyclonal Antibody
UOM: 1 * 1 mg


Supplier: LIOFILCHEM S.R.L.
Description: Antibiotic Tests, Vancomycin Va 5 µg

Catalog Number: (USBIF0011-24A)
Supplier: US Biological
Description: Anti-Factor Va, light chain, fragment E, 74kD Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase)) [clone: 3H368]
UOM: 1 * 50 µG


Catalog Number: (ENZOBMLSE3631000)
Supplier: ENZO LIFE SCIENCES
Description: Isolated from human plasma as prothrombin, and activated with Factor Xa, Factor Va, phospholipids, and calcium to yield a-thrombin.
UOM: 1 * 1 Vial

New Product


Catalog Number: (BOSSBS-9899R-A680)
Supplier: Bioss
Description: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilisation of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9899R-A750)
Supplier: Bioss
Description: Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilisation of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.
UOM: 1 * 100 µl


Catalog Number: (69/71962)
Supplier: Sartorius Balances
Description: Bench power supply SPS30W without cable, Input: 100 - 240 V; output: 24 V; current: 1,25 A; Power: 30 VA
UOM: 1 * 1 items


Supplier: LIOFILCHEM S.R.L.
Description: Multodisc with eight antimicrobial agents on a ring.

Catalog Number: (BOSSBS-7762R-CY5)
Supplier: Bioss
Description: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7762R-CY3)
Supplier: Bioss
Description: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7762R-A750)
Supplier: Bioss
Description: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-7762R-FITC)
Supplier: Bioss
Description: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-9507R-A647)
Supplier: Bioss
Description: Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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