You Searched For: Luff-Schoorl\\\'s+reagent

Description: Rabbit polyclonal to Keratinocyte differentiation associated protein.

Catalog Number: ABCAAB204583-100

UOM: 1 * 100 µl

Supplier: Abcam

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Description: Anti-Lysosome-associated Membrane Protein-1 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 9H151]

Catalog Number: USBIL9190-10F

UOM: 1 * 100 Tests

Supplier: US Biological

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Description: Anti-Adeno-Associated Virus 2, VP1, VP2, VP3 Mouse Monoclonal Antibody [clone: 5F165]

Catalog Number: USBIA0868-36K

UOM: 1 * 50 µG

Supplier: US Biological

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Description: FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.  SUBCELLULAR LOCATION: Cytoplasm; cytosol. Cell membrane. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. ALTERNATIVE PRODUCTS: 8 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Isoforms differ from each other by the presence or absence of up to 5 of the 15 exons. One of these optional exons contains the additional tau/MAP repeat. TISSUE SPECIFICITY: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. DEVELOPMENTAL STAGE: Four-repeat (type II) tau is expressed in an adult-specific manner and is not found in fetal brain, whereas three-repeat (type I) tau is found in both adult and fetal brain. DOMAIN: The tau/MAP repeat binds to tubulin. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments  and straight filaments, mainly composed of hyperphosphorylated forms of Microtubule-associated protein Tau. Defects in Microtubule-associated protein Tau are a cause of frontotemporal dementia and parkinsonism linked to chromosome 17, as well as a number of other neurodegenerative diseases.

Catalog Number: BSENM-1703-100

UOM: 1 * 100 µl

Supplier: Biosensis

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Description: Anti-Lysosome Associated Membrane Protein 1 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 9A179]

Catalog Number: USBIL9190-07K

UOM: 1 * 100 Tests

Supplier: US Biological

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Description: Anti-Adeno-Associated Virus 2, VP1, VP2, VP3 Mouse Monoclonal Antibody [clone: 9L4]

Catalog Number: USBIA0868-36L

UOM: 1 * 50 µG

Supplier: US Biological

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Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Catalog Number: BOSSBS-5164R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

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Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Catalog Number: BOSSBS-5164R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Catalog Number: BOSSBS-5164R-CY5.5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Catalog Number: BOSSBS-5164R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Anti-ETS1 associated protein II/EAPII Rabbit Polyclonal Antibody

Catalog Number: BIRBORB4458-100

UOM: 1 * 100 µG

Supplier: Biorbyt

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Description: Recombinant SARS-associated coronavirus (SARS-CoV) M protein (from <i>E. coli</i>)

Catalog Number: BIRBORB82444-1

UOM: 1 * 1 mg

Supplier: Biorbyt

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Description: Anti-PALLD (palladin, cytoskeletal associated Protein) Mouse Polyclonal Antibody

Catalog Number: ABNOH00023022-A01

UOM: 1 * 50 µl

Supplier: Abnova

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Description: Anti-Lysosome Associated Membrane Protein 2 Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy5®) [clone: 5K77]

Catalog Number: USBIL9190-14E

UOM: 1 * 100 Tests

Supplier: US Biological

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Description: Anti-LSM8 Homolog, U6 Small Nuclear RNA Associated Mouse Monoclonal Antibody [clone: 8C213]

Catalog Number: USBIL4603-48

UOM: 1 * 50 µG

Supplier: US Biological

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Description: Anti-Lipoprotein Receptor-related Protein Associated Protein 1, Low Density Rabbit Polyclonal Antibody (Biotin)

Catalog Number: USBIL2601-08C-BIOT

UOM: 1 * 200 µl

Supplier: US Biological

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