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Image Unavailable-BOSSBS-6767R-A488

Anti-PDC6I Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-6767R-A488)
Supplier: Bioss
Description: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6767R-A350

Anti-PDC6I Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-6767R-A350)
Supplier: Bioss
Description: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6767R-A680

Anti-PDC6I Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-6767R-A680)
Supplier: Bioss
Description: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
UOM: 1 * 100 µl
Product Image-664-0219

Dissolved oxygen sensors for industrial applications, OxyFerm FDA

Supplier: HAMILTON BONADUZ
Description: These electrochemical oxygen sensors are ideal for applications with high demands for hygiene, e.g. in pharmaceutical industry, in biotechnology and in foods & beverages production. The sensors are equipped with a FDA approved membrane for usage in hygienic processes. They can withstand steam sterilisation, autoclavation and CIP cleanings.

Product Image-WTWO109239

pH electrodes with single rod measuring chain, ProcessLine

Catalog Number: (WTWO109239)
Supplier: WTW ONLINE
Description: The special design of the process line electrodes makes them close to optimal in their accuracy, stability, speed and longevity to liquid electrolyte electrodes. For the use in pipelines, they can be installed into the replacement fitting CHEMtrac 830 M.
UOM: 1 * 1 items
Product Image-662-1701

pH combination electrodes, ProcessLine

Supplier: SI Analytics
Description: These electrodes are low maintenance sensors for heavy duty process applications in the chemical industry. They are ideally suitable for measuring media with extreme ionic strength - whether boiler feed water or brine - also in strongly oxidizing acid and alkali containing media.

Product Image-181-0159

VWR® VP 2 Autovac Chemically Resistant Vacuum System

Catalog Number: (181-0159)
Supplier: VACUUBRAND
Description: The VP 2 Autovac chemistry pumping unit, with vacuum controller, meets the demands of modern rotary evaporation. The hysteresis-free vacuum control prevents boiling retardation and foaming, therefore, ensuring consistently high process safety and an exceptionally high performance, even at low vacuum. This control enables detection of vapour pressure and fully automatic adjustment of the vacuum level to the process requirements without any user programming or intervention.
UOM: 1 * 1 items
Product Image-662-1833

Bio process sterilisable pH and ORP electrodes, SteamLine

Supplier: SI Analytics
Description: Autoclavable high-tech electrodes with outstanding electrical and physical performance characteristics guaranteeing exceptional accuracy and reliability over long periods of time. Can be used in demanding environments such as SIP treatment (Sterilisation in Place), and CIP cleaning (Clean in Place).

Image Unavailable-BOSSBS-13343R-A680

Anti-GGA1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-13343R-A680)
Supplier: Bioss
Description: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13343R

Anti-GGA1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13343R)
Supplier: Bioss
Description: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
UOM: 1 * 100 µl
Product Image-662-2061

pH electrodes for pharmaceutical and chemical industries, EasyFerm Plus

Supplier: HAMILTON BONADUZ
Description: The EasyFerm Plus electrodes are designed to withstand demanding applications in pharmaceutical and chemical industries. They are supplied with a pre-pressurised electrolyte which prevents the diffusion of sample into the sensor.

Image Unavailable-BOSSBS-13343R-A350

Anti-GGA1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-13343R-A350)
Supplier: Bioss
Description: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13343R-CY7

Anti-GGA1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-13343R-CY7)
Supplier: Bioss
Description: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
UOM: 1 * 100 µl
Product Image-662-2110

pH and ORP combination electrodes, TopLine

Supplier: SI Analytics
Description: TopLine electrodes combine reliable measuring results with a maximum dwell time. They were developed for a wide range of applications in the lab, field and processing of wastewater via emulsions, solutions with proteins, suspensions all the way to purely aqueous samples.

Image Unavailable-SPCMV1019-250ML

n-Vinylpyrrolidone/Styrene copolymer 38%, aqueous emulsion

Catalog Number: (SPCMV1019-250ML)
Supplier: Spectrum Chemical
Description: N-Vinylpyrrolidone/Styrene Copolymer, 38 Percent Aqueous Emulsion, also known as N-Ethenyl-2-pyrrolidone, is an organic compound with a 5-membered lactam linked to a vinyl group. It is used as the precursor to polyvinylpyrrolidone.
UOM: 1 * 250 mL
Image Unavailable-ABCAAB308334-100

Anti-VPS35 Rabbit Monoclonal Antibody [clone: HL1017]

Catalog Number: (ABCAAB308334-100)
Supplier: Abcam
Description: Anti-VPS35 Rabbit Monoclonal Antibody [clone: HL1017]
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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