You Searched For: gabrq

Catalog Number: (PRSI13-375)

Supplier: ProSci Inc.

Description: Anti-GABRB3 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI31-134)

Supplier: ProSci Inc.

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the gaba/benzodiazepine receptor and opening an integral chloride channel.

UOM: 1 * 100 µG

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Catalog Number: (PRSI50-212)

Supplier: ProSci Inc.

Description: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003).

UOM: 1 * 100 µl

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Catalog Number: (ABNOPAB6997)

Supplier: Abnova

Description: Goat polyclonal antibody raised against synthetic peptide of GALR3.

UOM: 1 * 100 µG

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Catalog Number: (ABNOPAB9680)

Supplier: Abnova

Description: Rabbit polyclonal antibody raised against a recombinant Gabra1.

UOM: 1 * 100 µG

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Catalog Number: (ABNOPAB14688)

Supplier: Abnova

Description: Rabbit polyclonal antibody raised against synthetic peptide of Gabbr2.

UOM: 1 * 100 µG

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Catalog Number: (ORIGTA329169)

Supplier: OriGene

Description: Anti-Gabra5 Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

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Catalog Number: (BOSSBS-12065R-HRP)

Supplier: Bioss

Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-12061R-A488)

Supplier: Bioss

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

UOM: 1 * 100 µl

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Catalog Number: (USBI035855-FITC)

Supplier: US Biological

Description: Anti-GABRA4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

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Catalog Number: (BOSSBS-13261R-A488)

Supplier: Bioss

Description: The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABP beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.

UOM: 1 * 100 µl

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Catalog Number: (USBI035863-FITC)

Supplier: US Biological

Description: Anti-GABRG2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

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Catalog Number: (USBI035864-AP)

Supplier: US Biological

Description: Anti-GABRG3 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

UOM: 1 * 200 µl

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Catalog Number: (USBI035860-AP)

Supplier: US Biological

Description: Anti-GABRB2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

UOM: 1 * 200 µl

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Catalog Number: (BOSSBS-12084R-A647)

Supplier: Bioss

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-3766R-FITC)

Supplier: Bioss

Description: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).

UOM: 1 * 100 µl

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