You Searched For: gabrq

Catalog Number: (BOSSBS-12080R-HRP)

Supplier: Bioss

Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

UOM: 1 * 100 µl

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Catalog Number: (USBIG1012-10K)

Supplier: US Biological

Description: Anti-GAB1 Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

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Catalog Number: (ABGEAP19379C)

Supplier: Abgent

Description: Anti-GAR1 Rabbit Polyclonal Antibody

UOM: 1 * 400 µl

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Catalog Number: (462-8120)

Supplier: GRANT INSTRUMENTS

Description: Gabled stainless steel lid, For: OLS26

UOM: 1 * 1 items

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Catalog Number: (ROCK112-401-C81)

Supplier: Rockland Immunochemicals

Description: Anti-GABA(A) Receptor gamma 2 (Rabbit) antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 46kDa in size corresponding 2-subunit of the GABAA receptor in Western blots of Rat brain extracts.

UOM: 1 * 50 µl

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Catalog Number: (PRSI45-654)

Supplier: ProSci Inc.

Description: Anti-GALR2 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI27-228)

Supplier: ProSci Inc.

Description: GABRG2 is a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

UOM: 1 * 50 µG

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Catalog Number: (PRSI16-916)

Supplier: ProSci Inc.

Description: Anti-GABRG2 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (PRSI14-612)

Supplier: ProSci Inc.

Description: Anti-GABRA6 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

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Catalog Number: (ANTIA84280-100)

Supplier: ANTIBODIES.COM

Description: Goat polyclonal antibody to GALR1 for ELISA and WB with samples derived from human.

UOM: 1 * 100 µG

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Catalog Number: (ANTIA84624-100)

Supplier: ANTIBODIES.COM

Description: Goat polyclonal antibody to GABRA4 for ELISA, WB and IHC with samples derived from human.

UOM: 1 * 100 µG

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Catalog Number: (ANTIA10423-100)

Supplier: ANTIBODIES.COM

Description: Rabbit polyclonal antibody to GABPA for WB, IHC and ICC/IF with samples derived from human, mouse and rat.

UOM: 1 * 100 µl

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Catalog Number: (ANTIA97519-100)

Supplier: ANTIBODIES.COM

Description: Rabbit polyclonal antibody to GALR2 for WB and ELISA with samples derived from Human, Mouse and Rat.

UOM: 1 * 100 µG

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Catalog Number: (PRSI57-799)

Supplier: ProSci Inc.

Description: For WB starting dilution is: 1:500.

UOM: 1 * 400 µl

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Catalog Number: (PRSI50-227)

Supplier: ProSci Inc.

Description: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.

UOM: 1 * 100 µl

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Catalog Number: (PRSI79-658)

Supplier: ProSci Inc.

Description: GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site. Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein. G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsynaptic inhibitions: presynaptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsynaptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to synaptic inhibition, GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation.

UOM: 1 * 100 µG

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