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Catalog Number: (621-0043)
Supplier: BUCHI
Description: M-569 Sample loader for capillary melting tubes
UOM: 1 * 1 items


Supplier: Merck
Description: MultiScreen column loader scraper

Catalog Number: (BUEF11071632)
Supplier: BUCHI
Description: Solid loader connection kit 1 * 1 items
UOM: 1 * 1 items


Catalog Number: (BUEF148634560)
Supplier: BUCHI
Description: FlashPure Empty Solid Loader Frits 40 g, (10pcs) 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (BUEF140000176)
Supplier: BUCHI
Description: FlashPure Empty Solid Loader Frits 80g, 10pcs 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (11069686.)
Supplier: BUCHI
Description: PURE SOLID LOADER TEST 1 * 20 items
UOM: 1 * 20 items


Catalog Number: (BUEF148634332)
Supplier: BUCHI
Description: FlashPure Empty Solid Loader 40g, incl. frits (10pcs) 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (BUEF148634551)
Supplier: BUCHI
Description: FlashPure Empty Solid Loader Frits 12 g, (20pcs) 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (BUEF140000157)
Supplier: BUCHI
Description: FlashPure EcoFlex Empty Solid Loader 80g, incl. frits (5pcs) 1 * 1 items
UOM: 1 * 1 items

New Product


Catalog Number: (BUEF148634331)
Supplier: BUCHI
Description: FlashPure EcoFlex Empty Solid Loader 12g incl. frits (20pcs) 1 * 1 items
UOM: 1 * 1 items

New Product


Supplier: Agilent
Description: The 5100 ICP-OES features a plug and play torch, and a simple and effective torch-loader mechanism. This automatically aligns the torch and connects the gases to ensure fast start-up and reproducible performance.

Supplier: Bel-Art Products, a Part of SP
Description: These PP plates are compatible with standard robotic work stations, such as Zymark, Tecan, Hamilton, Rosys and Beckman. To side load a Beckman BioMek® system, use side-loader collars. 2 ml deep wells permit serial dilution protocols unlike with standard microtitre plates.

Catalog Number: (621-0044)
Supplier: BUCHI
Description: M-565 is an advanced, automated instrument with video capability for professional quality control in a regulated environment. Offers all the features above but with the automated determination of melting and boiling points. The product is available as a 'Professional set' with or without the M-569 sample loader - please see below for details.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-0836R-A680)
Supplier: Bioss
Description: Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0836R-FITC)
Supplier: Bioss
Description: Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0836R-CY5.5)
Supplier: Bioss
Description: Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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