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Image Unavailable-BOSSBS-1370R-A647

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1370R-A647)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Image Unavailable-99311-0.1ML-F

Potassium ionophore I - cocktail A, Selectophore™ ion sensor material, Supelco®

Catalog Number: (99311-0.1ML-F)
Supplier: Merck
Description: Ready-to-use ion selective liquid for the preparation of microelectrodes in micropipettes
UOM: 1 * 0,1 mL

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Product Image-734-2953

VWR®, Single-Use Tank Liners, Medical Grade

Supplier: VWR Collection
Description: These tank liners are single-use bags with an open top, designed to fit in cylindrical vessels.

Certificates

Product Image-734-3306

VWR®, Single-Use Bioprocessing Bags

Supplier: VWR Collection
Description: Avantor single-use bioprocessing bags are designed to transfer and store your products throughout the drug manufacturing process. Made from proprietary FlexFilm™ material - a thick, co-extruded film featuring polyethylene inner and outer layers that provide extra resistance to a wide range of chemicals - Avantor single-use bags are supplied in a range of standard sizes to meet the needs of many bioprocessing applications.

Product Image-MFLX31201-64

Masterflex® Single-Use Sanitary Gaskets, TPE, Avantor®

Supplier: Avantor Fluid Handling
Description: Ensure a tight seal in your sanitary fluid line.

Certificates 3A Sanitary approval

Image Unavailable-81153-100MG

Poly(dimethylsiloxane) analytical standard, for GPC

Catalog Number: (81153-100MG)
Supplier: Merck
Description: Poly(dimethylsiloxane) [PDMS] is a polymer. It is a stable silicone rubber. It has been used as ion selective membrane for ion-sensitive field-effect transistors, as spring material in accelerometers, elastomer on a tactile sensor and as flexible encapsulation material in decouple sensors.
UOM: 1 * 100 mg
Image Unavailable-BOSSBS-1370R-CY5.5

Anti-ATM Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-1370R-CY5.5)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1370R-A555

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1370R-A555)
Supplier: Bioss
Description: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM: 1 * 100 µl
Image Unavailable-C5041-100MG

6-CFDA (6-Carboxyfluorescein diacetate, single isomer), Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY
Description: Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. Fluorescent wavelengths λex 492 nm; λemm 517 nm in 0.1 M Tris, pH 8.0.

Product Image-MFLX30719-04

Masterflex® Single-Use Filling Needles

Supplier: Avantor Fluid Handling
Description: A high-quality engineered solution for every application in the fill-finish workflow.

Certificates

Product Image-HACHISEF12103

Ion selective electrodes, Fluoride, IntelliCAL™

Supplier: Hach
Description: IntelliCAL™ ISEF121 is a digital combination fluoride ion selective electrode (ISE) with a non-refillable, single junction reference and built-in temperature sensor. The solid-state sensor design eliminates membrane replacement and allows for dry storage of the ISE.

Product Image-665-0247

inoLab® Multi 9310 IDS Multi-Parameter Meter (pH/Conductivity/DO), Bench

Supplier: WTW
Description: The inoLab® Multi 9310 is ideal for all laboratories that require complete documentation, or want to have the most efficient, error-free measurement processes. For the measurement of a single parameter from pH, conductivity and DO.

Image Unavailable-76470-110

VWR®, Sterile Masks

Catalog Number: (76470-110)
Supplier: VWR Collection
Description: VWR® made in USA sterile masks are an ideal option for single-use needs.
UOM: 1 * 200 items
Image Unavailable-VEPA3FSKS610506

Single Use Test Packs, Bowie and Dick Type

Catalog Number: (VEPA3FSKS610506)
Supplier: VP Medical Packaging
Description: Sterilisation indicator, Bowie-dick single use test pack (prime-pack)
UOM: 1 * 50 items

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Product Image-663-0356

VWR® pHenomenal® IDP 761-C Conductivity Cell

Catalog Number: (663-0356)
Supplier: VWR Collection
Description: This IDP (Intelligent Digital Probe) conductivity/temperature cell can be used with the pHenomenal® MD 8000 H and MD 8000 L multi-parameter meters.
UOM: 1 * 1 items
Image Unavailable-734-3361

VWR® Single Use 3D Tank Liners with Bottom Drain

Supplier: VWR Collection
Description: These tank liners are single-use bags with an open top, designed to fit in cylindrical vessels.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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